Hieronim Jakubowski was born in Szczecinek, Poland, in 1946. He was a Postdoctoral Fellow at the University of New Mexico, Albuquerque, NM, USA (with Robert B. Loftfield, 1975–1976) and a FEBS Fellow at the Hanover Medical School, Germany (with Günther Maas, April 1982–July 1982). He was an EMBO Fellow at the Imperial College of Science and Technology, London, UK (with Alan Fersht, November 1980–December 1980), where he discovered biological synthesis of the thioester homocysteine thiolactone during homocysteine editing by aminoacyl-tRNA synthetases. He took a Yeast Genetics and Molecular Biology Course at the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA (July 1987–August 1987). His work focuses on the fidelity of amino acid selection by tRNA synthetases, error-editing mechanisms in protein biosynthesis, and mechanisms of homocysteine incorporation into protein, as well as on homocysteine-containing proteins and their role in human cardiovascular and neurodegenerative diseases. He is currently a Professor of Microbiology and Molecular Genetics at New Jersey Medical School, Newark, NJ, USA, a Professor at the Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, and a Professor at the Department of Biochemistry and Biotechnology, University of Life Sciences, Poznan.