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Biomedical Research and Clinical Practice (BRCP)

Online ISSN: 2397-9631

(Founding Editors)

Kazuhisa Nishizawa

Teikyo University

Cory J. Xian

University of South Australia

Biomedical Research and Clinical Practice (BRCP) is an open access journal with comprehensive peer review policy and a rapid publication process. BRCP is a novel journal that will focus upon the latest developments in medical research and associated disciplines. This journal will provide an extensive coverage on physiology, biochemistry, microbiology, clinical and medical engineering and computational aspects related to biomedical sciences. This journal aims to disseminate information on physiology, biochemistry, clinical chemistry, biomedical engineering, biomedical informatics, genetics, biophysics, system biology, mathematical medicine, cell biology, molecular and structural biology, developmental biology, pathology, geriatrics, hepatology, hematology, microbiology, immunology, infectious diseases, dermatology, preventive medicine, nephrology, neurology, endocrinology, oncology, ophthalmology, orthopaedics, personalized medicine, pharmacology, radiology, nuclear medicine, regenerative medicine, rehabilitation, toxicology, dentistry and oral surgery with an emphasis on medical/clinical significance. BRCP renders a global platform for academicians and researchers to share their work in relevant fields of biomedicine.

BRCP will feature original research, review papers, clinical studies, editorials, expert opinion and perspective papers, commentaries, and book reviews.

Biomedical Research and Clinical Practice (BRCP) is composed of the following Specialty Sections

Allergy

Endocrinology

Molecular & Cellular Biomedicine

Pharmacology

Anesthesiology

Epidemiology

Nephrology

Physiology

Biochemistry

Forensic Medicine

Neurology

Plastic Surgery

Biomaterials

Gastroenterology

Neurosurgery

Psychiatry

Biophysics

Genetics

Obstetrics & Gynecology

Public Health

Biotechnology

Genomics

Ophthalmology

Pulmonary Diseases

Cancer & Clinical Oncology

Hematology

Oral & Maxillofacial Surgery

Radiology

Cardiovascular Diseases

Hepatology

Orthopedics

Rehabilitation

Clinical Chemistry

Immunology

Otolaryngology

Sports Medicine

Computational Biology

Infectious Diseases

Palliative Care

Surgery

Critical Care

Medical Economics

Parasitology

Tissue Engineering & Regenerative Medicine

Dentistry

Medical Engineering

Pathology

Toxicology

Dermatology

Metabolic Diseases

Pediatrics

Urology

Emergency Medicine

Microbiology

Pharmaceutics

Virology

BRCP welcomes direct submissions from authors: Attach your word file with e- mail and send it to submissions@oatext.com alternatively to editor.brcp@oatext.com

Please, follow the Instructions for Authors. In the cover letter add the name and e-mail address of 5 proposed reviewers (we can choose them or not).

Copyright is retained by the authors and articles can be freely used and distributed by others. Articles are distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published by BRCP, is properly cited.

Biomedical Research and Clinical Practice Editor in Chief Message


Kazuhisa Nishizawa


Dr Nishizawa is serving as Professor at the Department of Clinical Laboratory Science of the Teikyo University School of Medical Technology, Japan. After graduating from the University of Tokyo School of Medicine, Tokyo, and being qualified as a medical doctor in 1989, He started the research at the Division of Medicine, Department of Neurobiology, Institute of Brain Research, University of Tokyo Graduate School, and received the Ph.D. degree (medicine and physiology) in 1994. Although his qualification is medical, his current research focuses on computational biochemistry: biologically relevant processes of interactions between lipid membrane and proteins, ion channel dynamics, transporter dynamics, membrane fusion (viral and intracellular), and other pathological processes. His recent focus is on improving several force fields for molecular dynamics with an emphasis on membrane protein folding, which are of high relevance of current molecular medicine.

Prior to these chemical studies, Dr Nishizawa has wet-laboratory experiences in molecular biology of mRNA stability regulation in neuronal cells and T-lymphocyte immunobiology from 1993 to 1998, including his postdoc years at Dana-Farber Cancer Institute, Boston. He also conducted studies in molecular evolutionary genetics using numerical simulations from 1998 to 2002. In 2006, he served as the founding Chief of the Dept of Clinical Laboratory Science at Teikyo University.

With a publication record covering computational physical chemistry, neurobiology, immunobiology and molecular evolution, since 2010 he has been serving as an editorial board member of several journals including Journal of Biophysical Chemistry, BioMed Research International, and Computational and Mathematical Methods in Medicine, the latter providing a unique forum for interdisciplinary research between clinicians/experimentalists and theoreticians, focusing on collaborations across biomedical, clinical, and translational research areas.  Teaching many students in his courses of biochemistry, clinical chemistry and analytical chemistry, he emphasizes training the next generation of scientists who have ambitions to bridge across diverse medical disciplines.


Cory J. Xian


Dr Xian is a Research Professor and NHMRC Senior Research Fellow at University of South Australia. He has more than 25 years of experience in research on tissue growth and repair, growth plate biology and bone growth, bone repair and regeneration, cancer chemotherapy-induced bone defects, and osteoporosis. Dr Xian obtained his PhD in 1993 from Murdoch University; and his earlier research positions include those at Child Health Research Institute, University of Adelaide, Flinders University, and Women’s and Children’s Hospital. Dr Xian has over 140 peer-reviewed publications.

Kazuhisa Nishizawa


Dr Nishizawa is serving as Professor at the Department of Clinical Laboratory Science of the Teikyo University School of Medical Technology, Japan. After graduating from the University of Tokyo School of Medicine, Tokyo, and being qualified as a medical doctor in 1989, He started the research at the Division of Medicine, Department of Neurobiology, Institute of Brain Research, University of Tokyo Graduate School, and received the Ph.D. degree (medicine and physiology) in 1994. Although his qualification is medical, his current research focuses on computational biochemistry: biologically relevant processes of interactions between lipid membrane and proteins, ion channel dynamics, transporter dynamics, membrane fusion (viral and intracellular), and other pathological processes. His recent focus is on improving several force fields for molecular dynamics with an emphasis on membrane protein folding, which are of high relevance of current molecular medicine.

Prior to these chemical studies, Dr Nishizawa has wet-laboratory experiences in molecular biology of mRNA stability regulation in neuronal cells and T-lymphocyte immunobiology from 1993 to 1998, including his postdoc years at Dana-Farber Cancer Institute, Boston. He also conducted studies in molecular evolutionary genetics using numerical simulations from 1998 to 2002. In 2006, he served as the founding Chief of the Dept of Clinical Laboratory Science at Teikyo University.

With a publication record covering computational physical chemistry, neurobiology, immunobiology and molecular evolution, since 2010 he has been serving as an editorial board member of several journals including Journal of Biophysical Chemistry, BioMed Research International, and Computational and Mathematical Methods in Medicine, the latter providing a unique forum for interdisciplinary research between clinicians/experimentalists and theoreticians, focusing on collaborations across biomedical, clinical, and translational research areas.  Teaching many students in his courses of biochemistry, clinical chemistry and analytical chemistry, he emphasizes training the next generation of scientists who have ambitions to bridge across diverse medical disciplines.

Cory J. Xian


Biography Dr Xian is a Research Professor and NHMRC Senior Research Fellow at University of South Australia. He has more than 25 years of experience in research on tissue growth and repair, growth plate biology and bone growth, bone repair and regeneration, cancer chemotherapy-induced bone defects, and osteoporosis. Dr Xian obtained his PhD in 1993 from Murdoch University; and his earlier research positions include those at Child Health Research Institute, University of Adelaide, Flinders University, and Women’s and Children’s Hospital. Dr Xian has over 140 peer-reviewed publications.

Section Editor in Chiefs


Kevin D. Brown (Genetics)

Associate Professor
Department of Biochemistry and Molecular Biology
University of Florida
USA

Carmen Cuffari (Gastroenterology)

Associate Professor
Department of Pediatrics
The Johns Hopkins Children’s Center
USA

Hironobu Ihn (Dermatology)

Professor & Chairman
Department of Dermatology & Plastic Surgery
Kumamoto University
Japan


CHAN Sun On (Neurology)

Professor
School of Biomedical Sciences
Assistant Dean, Faculty of Medicine
The Chinese University of Hong Kong
Hong Kong

Rajeev Aurora (Computational Biology)

Associate Professor
Molecular Microbiology & Immunology
Saint Louis University School of Medicine
USA

Tetsuro Sasada (Cancer and Clinical Oncology)

Director
Cancer Vaccine Center
Kanagawa Cancer Center
Japan


Noah Isakov (Molecular & Cellular Biomedicine)

Chair
The Shraga Segal Department of Microbiology and Immunology
Ben Gurion University of the Negev
Israel

Luigi Iuliano (Clinical Chemistry)

Senior Associate Professor
Department of Internal Medicine
Sapienza University of Rome
Italy

Cory Xian (Tissue Engineering and Regenerative medicine)

Professor
School of Pharmacy & Medical Sciences
University of South Australia
Australia


Alessandro Mauriello (Cardiovascular Diseases)

Associate Professor
Department of Biomedicine and Prevention
University of Rome Tor Vergata
Italy

Thomas Müller (Psychiatry)

Professor
Department of Neurology
St. Joseph Hospital
Germany

Vahit Ozmen (Surgery)

Professor
Department of Surgery
Istanbul University
Turkey


Sanjib Das Adhikary (Anesthesiology)

Associate Professor Division Director of Regional Anesthesia and Acute Pain Medicine
Penn State College of Medicine
USA

Editorial Board


Robert Geoffrey Cooper

Professor of Medicine
Faculty of Health & Life Sciences
University of Liverpool
UK

Jiann-Der Lee

Professor
FIET
Department of Electrical Engineering
Chang Gung University
Taiwan

Kazuhisa Bessho

Professor and Chairman
Department of Oral and Maxillofacial Surgery
Graduate School of Medicine, Kyoto University
Japan


Ewa Szczepanska-Sadowska

Professor
Department of Experimental and Clinical Physiology
Medical University of Warsaw
Poland

Philip D. Cotter

Principal and Co-Founder of ResearchDx
Laboratory Director
Pacific Diagnostics Clinical Laboratory
USA

Howard A. Palley

Professor Emeritus and
Distinguished Fellow,
Institute for Human Services Policy
School of Social Work
University of Maryland
USA


Zhixiang Wang

Professor
Department of Medical Genetics
Faculty of Medicine and Dentistry
University of Alberta
Canada

Gianluca Serafini

Professor of Psychiatry
Faculty of Medicine and Psychology
Sapienza University
Italy

Alvin A Holder

Department of Chemistry and Biochemistry Old Dominion University
USA


Yoram Barak

Professor
Department of Psychiatry
Sackler School of Medicine
Tel-Aviv University
Israel

Yasuo Iwasaki

Professor
Department of Neurology
Toho University
Omori Hospital
Japan

Tzi Bun NG

Professor of Biochemistry
School of Biomedical Sciences,
Faculty of Medicine,
The Chinese University of Hong Kong
Hong Kong


Anvarhusein A. Isab

Professor
Department of Chemistry
King Fahd University of Petroleum & Minerals
Saudi Arabia

Serap YALIN

Associate Professor
Department of Biochemistry
Mersin University
Turkey

Natalia V. Gulyaeva

Professor and Head
Dept. of Functional Biochemistry of the Nervous System,
Russian Academy of Sciences
Russia


Krzysztof Roszkowski

Professor
Department of Oncology, Radiotherapy and Gynecologic Oncology
Nicolaus Copernicus University
Poland

Osmar Antonio Centurión

Professor of Medicine
Department of Health Sciences’ Investigation
Asuncion National University
Paraguay

Wen Qiu

Associate professor
Department of Immunology
Nanjing Medical University
P.R. China


Ben Chung-Lap Chan

Senior Research Coordinator
Institute of Chinese Medicine
Chinese University of Hong Kong
Hong Kong

David I.Mostofsky

Professor
Department of Psychological & Brain Sciences
Boston University
USA

Lawrence C. Perlmuter

Professor
Department of Psychology
Rosalind Franklin University of Medicine
USA


Lanchun Lu

Assistant Professor
Department of Radiation Oncology
The OHIO State University
USA

Esther Priel

Professor
Department of Microbiology , Immunology & Genetics
Ben-Gurion university of the Negev
Israel

Sivagnanam Thamilselvan

Associate Scientist
Department of Urology
Henry Ford Health System
USA


Harry Schroeder

Professor
Division of Clinical Immunology and Rheumatology
University of Alabama
USA

Annemarie Shibata

Associate Professor
Department of Biology
Creighton University USA

Oleg Nadashkevich

Professor
Department of Family Medicine
Lviv National Medical University
Ukraine


José Francisco Navarro

Professor
Department of Psychobiology and Methodology of Behavioural Science
University of Málaga
Spain

Maria Passafaro

Department BIOMETRA
CNR Institute of Neuroscience
Italy

Heung-Il Suk

Assistant Professor
Department of Brain and Cognitive Engineering
Korea University
South Korea


Tamer A Gheita

Professor
Department of Rheumatology and Clinical Immunology
Cairo University
Egypt

Xiao-Xin Yan

Professor
Department of Anatomy & Neurobiology
Central South University
China

Gamal Hassan El-Sokkary

Professor
Department of Zoology
Assiut University
Egypt


Vladan Bajic

Professor
Laboratory for Radiobiology and Molecular Genetics
Institute for Nuclear Research
Serbia

Ibrahim El-Sayed M. El-Hakim

Professor
Ain Shams University
Department of Oral and Maxillofacial Surgery
Egypt

Mahmoud A Hafez

Professor
Head of the Orthopaedic Unit
October 6 University Hospital
Egypt


Tarek Aboul-Fadl Mohamed Hassan

Professor
Department of Pharmaceutical Chemistry
Assiut University
Egypt

Turgay Celik

Head of Coronary Care Unit
Department of Cardiology
Gulhane Military Medical Academy
Turkey

Masoud Neghab

professor
School of Health
Shiraz University of Medical Sciences
Iran


Marcelo Rodrigues Azenha'

Professor at Funorp (Surgery)
Oral Surgeon - Stomatology Department
University of São Paulo
Brazil

Seung-Yup Ku

Professor
Department of Obstetrics and Gynecology
Seoul National University Hospital
South Korea

Jinyong Peng

Professor
College of Pharmacy
Dalian Medical University
China


Geoffrey Sperber

Professor Emeritus
Faculty of Medicine & Dentistry
University of Alberta
Canada

Ken KL Yung

Associate Head and Professor
Department of Biology
Hong Kong Baptist University
China

Ameen Khraisat

Professor
Department of Conservative Dentistry and Prosthodontics
University of Jordan
Jordan


P. Satyanarayana Murthy

Professor
ENT and Head & Neck Surgery
Pinnamaneni Siddhartha Institute of Medical Sciences and Research Center
India

Ashraf Ramadan Hafez Ibraheem

Professor
Head of Department of Orthopaedic Physical Therapy
Deraya University
Egypt

José Enrique Robles

Professor
Department of Urology
University of Navarra
Spain


Aditi Banerjee

Assistant Professor
Department of Pediatrics
University of Maryland School of Medicine
USA

Ahmet Eroglu

Professor
Department of Anesthesiology and Reanimation
Karadeniz Technical University
Turkey

Chen Yu

Investigator
Shenzhen Institutes of Advanced Technology
Chinese Academy of Sciences
China


Emad Tawfik Mahmoud Daif

Professor
Faculty of Oral & Dental Medicine
Cairo University
Egypt

Michel Bourin

Professor
Neurobiology of anxiety and mood disorders 98
University of Nantes
France

Sergey Savinov

Extension Associate Professor
Department of Biochemistry and Molecular Biology
University of Massachusetts
USA


Dr. Imtiaz A. Chaudhry

Ophthalmic Plastic & Reconstructive Surgery
Texas Medical Center
USA

Hom Nath Chalise

Asian College for Advance Studies
Purbanchal University
Nepal

Antonio G Tristano

Rheumatologist
Centro Medico Carpetana
Spain


Early View

Volume 2, Issue 3


Will be updated soon.

Current Issue

Volume 2, Issue 2


Cholesterol and saturated fatty acid stabilize dimerization of helical transmembrane peptides by lowering energy cost related to peptides desolvation from lipids upon dimerization: an insight from atomistic simulation

Manami Nishizawa Kazuhisa Nishizawa

Research Article-Biomedical Research and Clinical Practice (BRCP)

March 13, 2017


Joint Hypermobility Syndrome and Postural Orthostatic Tachycardia Syndrome (HyPOTS)

Dana Mandel Ali D. Askari Charles J. Malemud Artan Kaso

Research Article-Biomedical Research and Clinical Practice (BRCP)

March 25, 2017


Urgent surgical treatment for a huge metastatic tumor of the right lung via plastron thoracotomy: A case report

Ryuta Fukai Yoshihito Irie Yoshiaki Katada Hajime Arifuku

Case Report-Biomedical Research and Clinical Practice (BRCP)

March 27, 2017


Paracardiac mass in a 55-year-old female - a case report of right-sided spontaneous diaphragmatic hernia

Rakul Nambiar Archana Jayakumar Jayakumar Chinnathambi

Case Report-Biomedical Research and Clinical Practice (BRCP)

March 30, 2017


Circadian rhythms of angiogenic factors in skin and wound tissue in per2-mutant mice

Tomoaki Hoshi Yoko Toukairin Tomomi Arai Makoto Nogami

Research Article-Biomedical Research and Clinical Practice (BRCP)

April 14, 2017


Alteration of tumor markers may predict survival in colorectal cancer patients treated with TAS-102 or regorafenib as salvage-line chemotherapy: a single-institutional experience

Keiji Matsuda Keijiro Nozawa Kohei Ohno Yuka Okada Takahiro Yagi Mitsuo Tsukamoto Yoshihisa Fukushima Takuya Akahane Atsushi Horiuchi Ryu Shimada Tamuro Hayama Koichi Okamoto Takeshi Tsuchiya Junko Tamura Hisae Iinuma Yuko Sasajima Fukuo Kondo Shoichi Fujii Yojiro Hashiguchi

Article Type-Biomedical Research and Clinical Practice (BRCP)

April 15, 2017


Previous Issue

Volume 2, Issue 1


Coenzyme Q10 - gamma cyclodextrin complex is a powerful nutraceutical for anti-aging and health improvements

Yukiko Uekaji Keiji Terao

Research Article-Biomedical Research and Clinical Practice (BRCP)

January 03, 2017


Suppressive effect of mycolactone-containing fraction from Mycobacterium ulcerans on antibody production against co-administered antigens

Noriko Shinoda Hajime Nakamura Mineo Watanabe

Research Article-Biomedical Research and Clinical Practice (BRCP)

January 05, 2017


Biomedical research and clinical practice - your journal

Kazuhisa Nishizawa

Editorial-Biomedical Research and Clinical Practice (BRCP)

January 09, 2017


Extrinsic effectors regulating genes for plasmalogen biosynthetic enzymes in HepG2 cells

Ryouta Maeba Shin-ichi Nakahara

Research Article-Biomedical Research and Clinical Practice (BRCP)

February 03, 2017


Biofeedback training on university student's anxiety management: A systematic review

Paulo Chaló Patrícia Batista Anabela Pereira

Review Article-Biomedical Research and Clinical Practice (BRCP)

February 09, 2017


Infrared light as a potential therapeutic approach for neurodegeneration

Kazuhiro Nakamura Takayasu Kawasaki

Review Article-Biomedical Research and Clinical Practice (BRCP)

February 28, 2017


Archive


Volume 2

Cholesterol and saturated fatty acid stabilize dimerization of helical transmembrane peptides by lowering energy cost related to peptides desolvation from lipids upon dimerization: an insight from atomistic simulation

Manami Nishizawa Kazuhisa Nishizawa

Research Article-Biomedical Research and Clinical Practice (BRCP)

March 13, 2017


Joint Hypermobility Syndrome and Postural Orthostatic Tachycardia Syndrome (HyPOTS)

Dana Mandel Ali D. Askari Charles J. Malemud Artan Kaso

Research Article-Biomedical Research and Clinical Practice (BRCP)

March 25, 2017


Urgent surgical treatment for a huge metastatic tumor of the right lung via plastron thoracotomy: A case report

Ryuta Fukai Yoshihito Irie Yoshiaki Katada Hajime Arifuku

Case Report-Biomedical Research and Clinical Practice (BRCP)

March 27, 2017


Paracardiac mass in a 55-year-old female - a case report of right-sided spontaneous diaphragmatic hernia

Rakul Nambiar Archana Jayakumar Jayakumar Chinnathambi

Case Report-Biomedical Research and Clinical Practice (BRCP)

March 30, 2017


Circadian rhythms of angiogenic factors in skin and wound tissue in per2-mutant mice

Tomoaki Hoshi Yoko Toukairin Tomomi Arai Makoto Nogami

Research Article-Biomedical Research and Clinical Practice (BRCP)

April 14, 2017


Alteration of tumor markers may predict survival in colorectal cancer patients treated with TAS-102 or regorafenib as salvage-line chemotherapy: a single-institutional experience

Keiji Matsuda Keijiro Nozawa Kohei Ohno Yuka Okada Takahiro Yagi Mitsuo Tsukamoto Yoshihisa Fukushima Takuya Akahane Atsushi Horiuchi Ryu Shimada Tamuro Hayama Koichi Okamoto Takeshi Tsuchiya Junko Tamura Hisae Iinuma Yuko Sasajima Fukuo Kondo Shoichi Fujii Yojiro Hashiguchi

Article Type-Biomedical Research and Clinical Practice (BRCP)

April 15, 2017


Coenzyme Q10 - gamma cyclodextrin complex is a powerful nutraceutical for anti-aging and health improvements

Yukiko Uekaji Keiji Terao

Research Article-Biomedical Research and Clinical Practice (BRCP)

January 03, 2017


Suppressive effect of mycolactone-containing fraction from Mycobacterium ulcerans on antibody production against co-administered antigens

Noriko Shinoda Hajime Nakamura Mineo Watanabe

Research Article-Biomedical Research and Clinical Practice (BRCP)

January 05, 2017


Biomedical research and clinical practice - your journal

Kazuhisa Nishizawa

Editorial-Biomedical Research and Clinical Practice (BRCP)

January 09, 2017


Extrinsic effectors regulating genes for plasmalogen biosynthetic enzymes in HepG2 cells

Ryouta Maeba Shin-ichi Nakahara

Research Article-Biomedical Research and Clinical Practice (BRCP)

February 03, 2017


Biofeedback training on university student's anxiety management: A systematic review

Paulo Chaló Patrícia Batista Anabela Pereira

Review Article-Biomedical Research and Clinical Practice (BRCP)

February 09, 2017


Infrared light as a potential therapeutic approach for neurodegeneration

Kazuhiro Nakamura Takayasu Kawasaki

Review Article-Biomedical Research and Clinical Practice (BRCP)

February 28, 2017


Volume 1

Distinctive expression of TMEM132A and its regulation after the nerve injury in the DRG

Ghoshun Shimosato Kentaro Oh-hashi Yosuke Yamaguchi Fumimasa Amaya

Research Article-Biomedical Research and Clinical Practice (BRCP)

October 26, 2016


Perception and attitude of religious leaders and outpatients in Dhaka, Bangladesh with regard to Ayurvedic medicine

Yoshitoku Yoshida Yasuko Yoshida Md. Abdul Alim Zakia Alam Mohammad Asaduzzaman Manikdrs Shahabuddin

Research Article-Biomedical Research and Clinical Practice (BRCP)

October 31, 2016


DHA-enriched supplement ameliorates cancer-associated systemic inflammatory response via resolvin D1 production: a single institutional study.

Yasuhiko Mohri Koji Tanaka Hiroki Imaoka Chikao Miki Hiroyuki Fujikawa Tadanobu Shimura Yuji Toiyama Toshimitsu Araki Masato Kusunoki

Research Article-Biomedical Research and Clinical Practice (BRCP)

November 16, 2016


Factors regulating Th17 cells: a review

Reiko Seki Kazuhisa Nishizawa

Review Article-Biomedical Research and Clinical Practice (BRCP)

November 17, 2016


Comparison between resting energy expenditure measured by indirect calorimetry and metabolic rate estimate based on Harris-Benedict equation in septic patients

Jiro Kamiyama Tomonori Takazawa Akihiro Yanagisawa Masafumi Kanamoto Masaru Tobe Hiroshi Hinohara Fumio Kunimoto Shigeru Saito

Research Article-Biomedical Research and Clinical Practice (BRCP)

November 18, 2016


Unexpected inhibition of cervical carcinoma cell proliferation by expression of heat shock transcription factor 1

Jiro Kamiyama Tomonori Takazawa Akihiro Yanagisawa Masafumi Kanamoto Masaru Tobe Hiroshi Hinohara Fumio Kunimoto Shigeru Saito

Research Article-Biomedical Research and Clinical Practice (BRCP)

November 22, 2016


Enhanced Th17 responses with intestinal dysbiosis in human allergic, inflammatory, and autoimmune diseases

Jun Shimizu Noboru Suzuki

Review Article-Biomedical Research and Clinical Practice (BRCP)

June 13, 2016


Role of the LIV-1 subfamily of zinc transporters in the development and progression of breast cancers: A mini review

Tomoka Takatani-Nakase Chihiro Matsui Koichi Takahashi

Review Article-Biomedical Research and Clinical Practice (BRCP)

June 20, 2016


Effects of passive leg raising on cardiovascular functions as analyzed by fingertip pulse pressure profiles

Kenji Nemoto Takayo Kaiho Susumu Ito Koichi Yoshioka Akira Maki

Research Article-Biomedical Research and Clinical Practice (BRCP)

June 24, 2016


Mechanisms of immunosuppression by mesenchymal stromal cells: a review with a focus on molecules

Kazuhisa Nishizawa Reiko Seki

Review Article-Biomedical Research and Clinical Practice (BRCP)

July 23, 2016


Predictive biomarkers for diagnosis of minimal hepatic encephalopathy in patients with liver cirrhosis: A preliminary result in a single center study in Japan

Kazuyuki Suzuki Hidekatsu Kuroda Kei Sawara Yuichi Yoshida Keisuke Kakisaka Yuji Suzuki Akiko Suzuki Mio Onodera Takayoshi Oikawa Wang Tei Ryujin Endo Akinobu Kato Yasuhiro Takikawa

Research Article-Biomedical Research and Clinical Practice (BRCP)

July 26, 2016


Novel biosynthesis of monogalactosyl-alkylacyl glycerolipid in Mop8 fibroblast cells transfected with a ceramide galactosyltransferase gene

Ken-ichi Nagai Nobuyoshi Takahashi Yukio Niimura

Research Article-Biomedical Research and Clinical Practice (BRCP)

July 31, 2016


Cost-benefit analysis of the rubella vaccination in Japan to prevent congenital rubella syndrome: analyses from three perspectives

Tomoya Itatani Chika Honda Kazuo Hayakawa Kaoru Konishi

Research Article-Biomedical Research and Clinical Practice (BRCP)

April13, 2016


Automated and rapid system for detection of ALK rearrangement genes in non-small cell lung cancer based on a Quenching Probe method

Marifu Yamagishi Koji Tsuta Tatsunori Shimoi Yuko Tanabe Mitsuharu Hirai Takashi Kohno Kouya Shiraishi Takashi Nakaoku Kuniko Sunami Kenji Tamura Akinobu Hamada

Research Article-Biomedical Research and Clinical Practice (BRCP)

April25, 2016


Acute influence of mild hyperbaric oxygen at 1.25 atmospheres absolute with normal air on mitochondrial enzymes and PGC-1α mRNA levels in rat skeletal muscle

Naoto Fujita Tomoka Tomioka Miharu Ono Masataka Deie

Research Article-Biomedical Research and Clinical Practice (BRCP)

April25, 2016


Low-grade endotoxemia, diet, and gut microbiota – an emphasis on the early events leading to dysfunction of the intestinal epithelial barrier

Kazuhisa Nishizawa

Review Article-Biomedical Research and Clinical Practice (BRCP)

April29, 2016


Exophytic glioblastoma multiforme originating from the medulla oblongata

Yoshifumi Horita Masahiko Wanibuchi Yukinori Akiyama Kengo Suzuki Yoshinori Omori Satoshi Iihoshi Satoko Ochi Takeshi Mikami Nobuhiro Mikuni

Research Article-Biomedical Research and Clinical Practice (BRCP)

May 16, 2016


Prolonged induction of warfarin metabolism and a paradoxical INR response in a mitral valve replacement patient receiving rifampicin for infective endocarditis

Jessica Dawson Maneesha Dedigama David J Elliot Michael Sorich Arduino A Mangoni Andrew Rowland

Case Report-Biomedical Research and Clinical Practice (BRCP)

May 31, 2016


Biomedical research and clinical practice - open access

Kazuhisa Nishizawa

Editorial-Biomedical Research and Clinical Practice (BRCP)

February 05, 2016


Effectiveness of epidural and systemic postoperative analgesia in laparoscopic urologic surgery - A retrospective cohort study

Conchita Monsalve Ana Bogdanovich Laura Izquierdo Clara Hernández-Cera Carme Busquets Sebastián Videla

Research Article-Biomedical Research and Clinical Practice (BRCP)

February 05, 2016


An in vitro study on the effect of synthesized tin(IV) complexes on glioblastoma, colorectal, and skin cancer cell lines

Jennie L Williams Lesley C Lewis-Alleyne Melinda Solomon Long Nguyen Robert Johnson Jennifer Vital Ping Ji John Durant Camille Cooper Patrice Cagle Patrick Martin Don VanDerveer William L Jarrett Alvin A Holder

Research Article-Biomedical Research and Clinical Practice (BRCP)

February 15, 2016


Gene as a risk factor for type 2 diabetes mellitus and its related complications

Alice JayaPradha Cheekurthy C Rambabu Amit Kumar

Research Article-Biomedical Research and Clinical Practice (BRCP)

February 29, 2016


Development of a cranium-infection rat model for artificial bone implantation

Yoshikazu Inoue Yoshiaki Sakamoto Hiroko Ochiai Yohko Yoshimura Takayuki Okumoto

Research Article-Biomedical Research and Clinical Practice (BRCP)

March 08, 2016


Can robotic-based top-down rehabilitation therapies improve motor control in children with cerebral palsy? A perspective on the CPWalker project

Lerma Lara S Martínez Caballero I Bayón C del Castillo MD Serrano I Raya R Belda-Lois JM Martín Lorenzo T Moral Saiz B Ramírez Barragán A Parra Mussin E Loma-Ossorio García M Pérez-Somarriba A Rocon E

Perspective-Biomedical Research and Clinical Practice (BRCP)

March 28, 2016


External Databases & Indexes


Submit Manuscript


BRCP welcomes direct submissions from authors: Attach your word file with e- mail and send it to submissions@oatext.com alternatively to editor.brcp@oatext.com

Publication Charges


Special Issues


  • "Gut Microbiota and Health – from Biology to Clinics"


    Editor Affiliation:

    Kazuhisa Nishizawa
    Teikyo University
    Japan

    Description of the Special Issue: Recent studies highlighted the central role of the gut microbiota in our health and diseases. High-fat-diet as a factor for dysbiosis and for entrance of endotoxin form the gut to the circulation, worsening atherosclerosis, is now known. Prebiotics/probiotics are being attempted in many clinical settings, and characterizations of specific bacterial species for potential usefulness are underway, propelled by technical improvements in metagenomics and in animal models. This special issue aims to widely discuss gut microbiota, from basics such as immunity-microbiota interplay, to pathology of diseases, and to therapeutic frontiers.


  • Gene and protein expression in cancers: small science vs systematic approaches


    Editor Affiliation:

    Kazuhisa Nishizawa
    Teikyo University
    Japan

    Improvements of technologies in DNA sequencing and mass spectrometry analysis propelled high-throughput studies in cancer biology. Yet, in clinics only a limited number of genes/proteins are considered as predictive markers, which have primarily been characterized from biological interests in a small science format, suggesting importance of considering strengths and weaknesses of various approaches as a source for prognostic or predictive markers for cancer treatment.  In this special issue, studies of any types on gene/protein expression in cancers are welcome.  We welcome cases of  characterization of specific genes in a conventional way of biological research, but, insights derived from more systematic and integrated, omics-based approaches may be discussed as well.  Challenges in bridging these two extremes would become the ultimate theme to be discussed.


  • Effects of long-chain n-3 PUFAs: biology and clinical relevance


    Editor Affiliation:

    Kazuhisa Nishizawa
    Teikyo University
    Japan

    Consumption of long-chain n-3 (omega-3) polyunsaturated fatty acids (PUFAs) of marine origin, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), has beneficial effects on our health in many settings. Reflecting their multifaceted and multilayers functions, research activities related to these PUFAs are diverse. This special issue aims to consider a wide range of studies on long chain n-3 PUFAs, ranging from biological, immunological, epidemiological, and clinical settings, including autoimmune diseases, cardiovascular diseases, cancers, and metabolic syndrome. While their overall anti-inflammatory effects are clear in simpler systems, their clinical translations are often showing no or marginal effects. We welcome not only positive but also negative findings and discussions about controversial subareas.  In particular, EPA vs DHA ratio, n-6 vs n-3 ratio, effects showing dependency on age, stage of diseases and genetic factors relevant to fine tuning of supplementation protocols may become central topics of this issue.


  • Advances in pathophysiology and prevention of cancer treatment-induced side effects


    Editor Affiliation:

    Cory J. Xian
    University of South Australia
    Australia

    With the greater success in treating cancers, the focus has now turned to reducing the associated toxicities. Cancer treatment-induced side effects include acute tissue damages such as gastrointestinal damage (mucositis) and bone marrow damage (marrow cell depletion), and chronic side effects such as skeletal damage (bone loss, osteonecrosis, bone marrow adiposity and fractures) and metabolic disorders. These are important issues that can impact significantly on cancer treatment itself (dosage and success), patient hospitalisation and quality of life for patients and survivors. Due to the commonality of the problems (with increasing numbers of cancer patients and/or survivors suffering from these issues) and lack of effective treatments, further work is required to understand the pathophysiology of cancer treatment-induced side effects and to develop therapies for their prevention and/or treatment. The purpose of this special issue is to report advances in clinical and preclinical (molecular/cellular research/animal model) studies into pathophysiology of cancer treatment-induced tissue damage and repair, new treatment strategies for preventing or treating these acute or chronic side effects. Original research or review articles are invited for this special issue.