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Food elimination diet among college students affecting physical performance and learning

Susan Stockton

Department of Nutrition and Kinesiology, University of Central Missouri Warrensburg, USA

E-mail : sstockton@ucmo.edu

DOI: 10.15761/CRT.1000115

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Abstract

Introduction

 A follow-up study conducted among collegiate athlete’s was performed to determine if an IgG directed 14-day food elimination diet (FED) would have a positive impact on grip strength, 100(x3) meter run time, waist and hip measurements and responses to the Learning Difficulties Assessment among enrolled physically active college students.

Methods

 A quasi-experimental, nonrandomized, repeat measure study without a control group was conducted at the primary investigators educational institution. Students (n=49) were invited to participate in the study where baseline IgG food sensitivity was obtained using a Dried Blood Spot (DBS) specimen (Great Plains Laboratory, Lenexa, KS, USA). Students performed grip strength, waist measurement, hip measurement, 100 meter run, and Learning Difficulties Assessment (LDA) survey. A registered dietitian met with subjects to guide the 14-day food elimination diet based on results of the DBS specimen.

Results

 Descriptive statistic findings revealed that physical measures, e.g., run time, grip strength, and waist circumference for males and females as well as 19 of 23 items on the Learning Difficulties Assessment were improved after the two week food elimination diet.

Discussion

 Although the grip strength did not achieve statistical significance human physiologic gains as well as athletic competition (strength, run time) are measured on a less rigid model for determining improvement such that small differences reflect positive changes. The LDA did reveal some significant changes post FED and contributes to the growing body of literature about the gut brain connection.

Conclusions

 Expanding this study to include individuals enrolled in higher education without the prerequisite of membership on a collegiate athletic team revealed improvement in physical strength, run time, biometrics and responses on the Learning Difficulties Assessment survey compared to the initial pilot. Current research supports the relationship between gut health and brain function. Further study of eliminating specific foods based on IgG food sensitivity impacting cognition as well as physical prowess is warranted.

Key words

 IgG-directed food sensitivity, gut inflammation, physical performance, cognition

Introduction

Exploding in the scientific literature is research surrounding human surface mucosal and intestinal (gut) microorganisms. The ensemble of genes in these intestinal microbe populations constitutes the human microbiomec [1]. Using the search terms “human microbiome” within Google Scholar revealed 26 300 articles published since 2011. The Human Microbiome Project has further identified and classified the species and enzymes relevant to the intestinal flora [2]. Thus, the influence of the microbiome in health and disease continues to mount.

One of the largest longitudinal studies conducted by MIT, Harvard, and Massachusetts General Hospital found a correlation between changes in gut microbiota and the initiation of Type I Diabetes Mellitus [3]. This study found a three way link between antibiotic use during infancy, changes in gut bacteria, and disease states later in life. Specifically examined in their longitudinal study was the mode of maternal delivery and feeding of newborns resulting in variant populations of microbiota in the infants’ intestinal tract. Results also state that imbalances in the gut microbiome have been associated with infectious diseases, allergies, autoimmune disorders and obesity later in life [3]. Pediatric antibiotic usage has been found to induce imbalances in the gut microbiota [4]. Childhood antibiotic use, whether over-the-counter or by prescription, is linked to gut microbiome changes and possibly diseases later in adulthood [5]. Critical to health and well-being is the variety and ratio of gut microbiota. When this microbial milieu is altered food sensitization (a precursor to gut inflammation) and food allergy can result [6].   

Information from the investigation of the human microbiome suggests that therapeutic dietary interventions may be of benefit [7]. Along with dietary modifications may be strategies of immune modulation and microbiota restorative therapies to alter disease course outcomes [8]. According to Khanna and Tosh (2014) several disease states, such as attention deficit/hyperactivity disorder, autism, chronic fatigue syndrome among others, may have their pathogenesis from disorganized relay of communication between the gut immune system and the brain [9]. Dysregulation of the gut-brain axis may be the model for such disorders as irritable bowel syndrome via the hypothalamus-pituitary-adrenal axis where disruption of appropriate cross-talk between brain and gut exist [10]. Hornig posits that “microbes might participate in the pathogenesis of neuropsychiatric illness (depression) by triggering the production of autoantibodies that bind to brain targets” [11].

Considering the plethora of agents that may impact the optimal functioning of the human digestive system, e.g., medications, processed food intake, satisfactory digestive enzyme production and release, chemical toxins in food and water, electromagnetic radiation, emotional stressors, sleep patterns, overuse of antacids, antihistamines, histamine-2-blockers all can have deleterious effects [12]. When digestion is impaired resulting in partially digested food, such as proteins and peptides, the gut microbiota changes. Altered gut microbiota release endotoxins known as lipopolysaccharides. The mechanism by which lipopolysaccharides cause inflammation is through opening tight junctions leading to damaged occludin, zonulin, and actinomycin which then allows these undigested proteins and peptides to cross the intestinal mucosal layer, migrate to regional lymph nodes and enter the blood stream [13]. Once in the blood stream these proteins and peptides can bind to tissues initiating an immune response and autoimmunity [12].

Similar to the components that predispose to disruption of the digestive process are factors that contribute to systemic inflammation, e.g., poor dietary choices, physical inactivity, obesity, smoking, excessive alcohol consumption, altered gut permeability, dental caries, quality sleep, and vitamin D deficiency [14]. An estimated 100 million people are afflicted with food-related inflammatory conditions worldwide [15]. Concomitantly, an inflamed gut displays diminished diversity and complexity, compromising immune responsiveness and homeostasis [16]. To address this distortion within the digestive system manipulating the microbiota through diet may provide a viable avenue of health benefits. Vojdani (2015) states that the gold standard for identifying dietary contributors to gut imbalance and systemic inflammation may be with food reactions via the elimination-provocation diet protocol [13]. One specific test to identify aggravating foods in the diet is with Immunoglobulin G (IgG) antibody food antigen reaction. Shaw (2014) explains that IgG antibody food sensitivity/allergy testing is an effective means of isolating aggravating foods due to IgG1, IgG2, and IgG3 not exchanging heavy and light chains forming bispecific antibodies, rather these antibodies form large immune complexes contributing to inflammation [17].

Others feel that not enough research has been conducted to confirm the specificity of IgG antibody testing for confirming food allergy or other clinically meaningful outcomes [13,18]. Most all research has addressed correlation between gut dysbiosis and disease states. This study examined a 14-day food elimination diet based on IgG directed food sensitivity test with repeat biometric, cognitive, and physiologic measures to determine if this brief intervention could influence significant physical and learning parameters towards optimizing physical and mental performance.

Methods

During the spring 2015 semester currently enrolled college students (mean age 21.05 y) were invited to participate in this study. Research study announcements were made from principle investigators in their classes and shared with other faculty in the department. Institutional Review Board approval was obtained and informed consent documents were shared with all subjects prior to data collection by the principle investigators at their teaching institutions. As this arm of the study included those individuals that were not currently members of an athletic team the additional Physical Activity Readiness Questionnaire (PAR-Q) was added. Similar to the distribution of males and females at the principle investigators institution there were 25 female and 18 males completing all components of the study (N=43).

A one-group repeated measures, quasi-experimental follow-up study without a control group was conducted to see if extending the subject pool to physically active college age students rather than exclusively college athletes performed previously would result in significant changes in dependent variables of grip strength, waist circumference, hip circumference, 100-meter run time, and responses on the Learning Difficulties Assessment (LDA). Subjects electing to participate met with the principle investigators to complete consent forms, demographic survey, LDA, perform seated or standing grip strength using a hand-dynamometer (Lafayette Instruments Model J00105), 100-meter run time (indoor track), and provide dried blood spot (DBS) specimen for IgG analysis of 93 foods and Candida albicans. Subjects were allowed to ask questions about the study and instructed to meet with a registered dietician after IgG analysis results were received. During the meeting with the registered dietitian subjects were counseled on how to follow a 14-day food elimination diet based on their IgG antibody food antigen reaction report results. Students were also asked to keep a record of the foods consumed during the 14-day food elimination trial.

Results

Data from all subjects were entered into the SPSS vs. 19 (IBM Corp. Armonk, New York) statistical software program for analysis. Descriptive and non-parametric (one sample k-repeated measures) statistics were collected (Table 1). Of the physical measures both male and female waist circumference decreased and five of 23 items on the LDA increased significantly post intervention (Table 2). Achieving statistical significance was an improvement in 100 meter run time, initial x = 17.64 seconds, s.d. = 2.45 and after 14-day food elimination diet (FED) x = 17.07, s.d. = 2.00, p = .011. The comprehensive IgG Food Allergy test plus Candida albicans, Saccharomyces cerevisiae dry blood spot food antigens and Candida scales can be viewed in Table 3. The LDA used a 5-point Likert like scale with 1 representing agree completely and 5 representing disagree completely [19]. Data from the dairy and grains portions of the DBS are included for average values with this population (Table 3) as the majority of reactivity was found within these food groups. Examples from the values from the Candida albicans, Saccharomyces cerevisiae food items are also included. A sample DBS report is included as Appendix A.

Item

Pretest

Mean ± SD

Posttest

Mean ± SD

Aymp. Sig.

(p <.05)

Pretest; posttest

Run (N=43)(100mx3)

51.37±10.79

51.21±6.02

.011

Grip Strength (n=26)

94.04±21.32

98.98±24.55

.053

Waist (male n=13)

33.77±1.75

33.27±2.13

.043

Waist (female n=13)

30.62±3.03

29.54±2.74

.014

Hip (male n=13)

39.04±3.72

38.54±3.60

.372

Hip (female n=13)

37.65±2.30

36.96±1.76

.057

Remember (N=43)

3.35±.098

3.67±.094

.041

LstnLect

3.25±1.21

3.46±1.03

.117

LstnClass

3.67±1.06

3.90±1.04

.056

LostLect

3.46±1.22

3.53±1.00

.773

NotesLct

3.88±1.11

4.07±1.10

.227

RmrbTold

3.88±1.05

4.04±0.90

.266

DstrcTlk

3.14±1.17

3.49±1.14

.057

Daydream

3.30±1.16

3.40±1.14

.489

SnsLect

4.07±0.98

4.32±0.71

.033

SpknDir

3.93±0.96

4.02±0.80

.501

Undrstnd

4.11±0.79

4.37±0.76

.022

WrdsCnfs

4.40±0.65

4.46±0.59

.513

RptDir

3.60±1.25

3.65±1.23

.869

CnfsSay

3.62±1.17

3.72±1.11

.462

SeeTalk

3.60±0.88

3.67±1.04

.647

TakeNtes

3.88±1.05

3.93±1.06

.624

LseCnctr

3.35±1.17

3.46±0.96

.429

Cncntrte

3.65±1.15

3.70±1.06

.728

PartWrds

3.86±1.12

3.81±1.05

.858

RetainRd

3.46±1.16

3.32±1.15

.235

DistrcRd

2.67±1.27

2.58±1.28

.640

RmbrRd

3.04±1.33

3.44±1.18

.004

ReadTime

2.84±1.46

3.39±1.24

.001

Table 1.   Mean and Standard Deviation Data from Food Elimination Diet Study

Item

Rank

N

Mean Rank

Z

Asym Sig  (p<.05)

GripStr2-GripStrg

Neg.

8

11.38

-1.93

0.053

 

Pos.

17

13.76

 

 

    RunTime2-RunTime

Neg.

30

20.90

-2.55

0.011

      

Pos.

11

21.27

 

 

WaistM2-WaistM

Neg.

5

4

-2.02

0.043

                                   

Pos.

1

1

 

 

WaistF2-WasitF

Neg.

10

7

-2.45

0.014

 

Pos.

2

4

 

 

HipMale2-HipMale

Neg.

6

5

-0.89

0.372

 

Pos.

3

5

 

 

HipFem2-HipFem

Neg.

7

6.57

-1.9

0.057

 

Pos.

3

3

 

 

Remb2-Remember

Neg.

7

10.57

-2.05

0.041

 

Pos.

16

12.63

 

 

LstnLec2-LstnLec

Neg.

9

9

-1.56

0.117

 

Pos.

13

13.23

 

 

LstnCls2-LstnClss

Neg.

6

8.5

-1.91

0.056

 

Pos.

13

10.69

 

 

LostLec2-LostLect

Neg.

9

11.94

-0.29

0.773

 

Pos.

12

10.29

 

 

NotesLec2-NotesLct 

Neg.

6

9.83

-1.21

0.227

 

Pos.

12

9.33

 

 

RembrTld2-Rmrbtld

Neg.

8

10.63

-1.11

0.266

 

Pos.

13

11.23

 

 

DstrcTk2-DstrcTlk

Neg.

8

14.06

-1.91

0.057

 

Pos.

19

13.97

 

 

Daydrm2-Daybream

Neg.

7

10.07

-0.69

0.489

 

Pos.

11

9.14

 

 

SnsLect2-SnsLect

Neg.

3

5.5

-2.14

0.033

 

Pos.

10

7.45

 

 

SpknDir2-SpknDir

Neg.

8

6.94

0.67

0.501

 

Pos.

8

10.06

 

 

Undrstd2-Undrstnd

Neg.

4

8

-2.3

0.022

 

Pos.

13

9.31

 

 

WrdsCnf2-WrdsCnfs Neg.

Neg.

8

9

-0.65

0.513

 

Pos.

10

9.9

 

 

RptDir2-RptDir

Neg.

11

14.23

-0.16

0.869

 

Pos.

14

12.04

 

 

 

 

Item

 

 

Rank

 

 

N

 

 

Mean Rank

 

 

Z

 

 

Asym. Sig (p<.05)

 

 

CnfsSay2-CnfsSay

 

 

Neg.

 

 

9

 

 

9.61

 

 

-0.73

 

 

0.462

 

Pos.

11

11.23

 

 

SeeTalk2-SeeTalk

Neg.

13

17.38

-0.46

0.647

 

Pos.

18

15

 

 

TkeNtes2-TakeNtes

Neg.

11

11.18

-0.49

0.624

 

Pos.

12

12.75

 

 

LseCnct2-CseCnctr

Neg.

12

11.17

-0.79

0.429

 

Pos.

13

14.69

 

 

Cncntrt2-Cncntrte

Neg.

11

11.59

-0.35

0.728

 

Pos.

12

12.38

 

 

PartWrd2-PartWrds

Neg.

14

14

-0.18

0.858

 

Pos.

13

14

 

 

RetnRd2-RetainRd

Neg.

12

11.17

-1.19

0.235

 

Pos.

8

9.5

 

 

DistrRd2-DistrcRd

Neg.

16

12.94

-0.47

0.64

 

Pos.

11

15.55

 

 

RmbrRd2-RmbrRd

Neg.

5

10

-2.87

0.004

 

Pos.

18

12.56

 

 

Rdtime2-ReadTime

Neg.

4

8.5

-3.3

0.001

 

Pos.

19

12.74

 

 

Table 2. Repeat Measure Analysis of Food Elimination Diet Data

Item

Minimum

Maximum Mean

SD

Food Items

Casein

1.14                

11.29

4.50

2.47

Cheese

1.10

10.42

4.56

2.30

Goat Cheese

0.99

6.61

2.52

1.20

Milk

1.17

8.91

3.72

2.00

Moz. Cheese

0.93

9.37

3.18

1.90

Whey

1.28

8.61

4.16

2.07

Yogurt

1.17

9.03

3.73

2.08

Gliadin

1.20

9.82

3.69

1.95

Wheat Gluten

0.98

8.43

3.76

1.72

Wheat

0.95

7.43

3.17

1.78

Candida Items

Candida albicans

1.12

19.21

8.22

4.22

Sugar

1.07

3.47

1.54

0.40

Baker’s Yeast

1.33

13.35

3.94

2.26

Brewer’s Yeast

1.22

12.77

3.22

2.11

Table 3.  Sample results from the Comprehensive IgG Food Allergy Test ™ (N=43)

Food Items Scale=Not Significant 1.00-1.99; Low 2.00-3.49; Moderate 3.50-4.99; and High >5.00 while the ranges for the Candida scale were Not Significant <3.49; Low 3.50-6.99; Moderate 7.00-14.99; and High >15.00.

Discussion

Expanding the study to include students from the general university population supported previous findings with the LDA for “I hear what someone says: I just do not remember what was said” having statistical significance post intervention n = 43, z = -2.05, p = .041 [19]. Other LDA items revealed unique attribute changes from the prior study, including the following (N = 43):

•No matter how hard I try, lectures do not make sense to me, z = -2.14, p = .033,

•I have a hard time understanding what people are saying, z = -2.30, p = .022,

•Even when I am concentrating I have trouble remembering what I just read, z = -2.87, p = .004

•It is difficult for me to read for more than 10-20 minutes, z = -3.30, p = .001. Improving students’ ability to understand, read, and remember after FED may encourage positive dietary habits and less academic stress in this population. Although the time frame for this study was very brief there were significant changes in waist measurements for both males and females following the FED, males: z = -2.02, p = .043 and females: z = -2.45, p = .014. These findings contribute to the health measure of fitness for waist hip ratio, smaller girth indicating a possible decrease in gut inflammation, and less abdominal adipose an important marker for positive health outcomes.

In the physical competitive arena a split second or one pound can mean the difference between placing in the top of the field or not. The run time did express statistical significance as any improvement in run time can be a major contributor to success. Some subjects remarked that they “felt” less out of breath following the run test and that they “felt” more strength equally in both arms although both arms were not examined in this study. The grip strength test was also improved after FED, though not statistically relevant. Given that the demographic survey associated with this study did not ask about infant antibiotic usage, hours of sleep, exposure to sun during the recommended hours of the day, or current dental caries these are a few of the factors that need to be addressed in future studies. Due to lack of incentives/participation recruitment efforts/grant funding as well as time constraints involved with completing the requirements for this study within one academic semester, a control group was not included. For the future the researchers would like to include a control group, extend the timeframe of the FED to four weeks, and if possible provide the specific foods based on the subjects IgG reactivity report. With the overwhelming volume of research dedicated to the connection between the gut and the brain as well as the blossoming field of personalized medicine geared toward effecting optimal health outcomes, providing assessments such as the IgG food antigen/ Candida albicans, Saccharomyces cerevisiae would be a valid means to effect both of these emerging fields of study surrounding the human gut microbiome influence on cognition and physical prowess. Examining the sequence of the study within an academic semester may also contribute to understanding facets of the diet/gut/learning interaction process that facilitates both academic and physical performance for ideal health gains. This study contributes to the literature of benefit potential and ability to draw conclusions toward FED improving physical performance, LDA scores, and body metrics.

2021 Copyright OAT. All rights reserv

Practical application

This study supports the necessity for individuals, especially young adults whose physiology can respond with large gains in health with minimal dietary effort/alterations, to examine more closely their current food intake. Personalizing the diet using tests such as the IgG antibody/food antigen reaction to guide consumption can yield surprising and positive results among college students whether collegiate athlete or not [20]. Cost for lab testing may be a deterrent for college students and the findings indicate that excluding dairy and grains may be warranted for the majority of students [21]. Future investigation into the components within these food groups (dairy and grains) that contribute to IgG reactivity is an area for examination. Self-evaluation by means of exclusion/provocation of food items may also benefit young adults for improved health gains and can be conducted using non-invasive means as an estimate of reactivity between subject and food item [22] Since the preponderance of evidence concludes that the gut microbiota affects physiology in disease and is necessary for homeostasis this avenue of specificity for food selection may be the next strategy for optimizing human performance [23,24].

Conclusion

This study supports the present day findings of altering food consumption based on a host specific assessment of IgG antibody food antigen evaluation to improve selected areas of learning difficulty, body metrics (waist circumference) and potential for faster run speeds.

Acknowledgements

The authors would like to thank Great Plains Laboratory, Lenexa, KS USA for their cooperation and reduced fee for processing the Comprehensive IgG food allergy and Candida albicans+Sacchromyces cervasiae dried blood spot specimens as well as the University of Central Missouri for grant support for this study. The results of the current study do not constitute endorsement of the product by the authors or the journal.

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Editorial Information

Editor-in-Chief

Jalal K. Ghali Mercer University

Article Type

Research Article

Publication history

Received date: July 07, 2015
Accepted date: November 07, 2015
Published date: November 15, 2015

Copyright

©2015 Stockton S.This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Citation

Stockton S (2015) Food elimination diet among college students affecting physical performance and learning. Clin Res Trials 1: doi: 10.15761/CRT.1000115

Corresponding author

Susan Stockton

Department of Nutrition and Kinesiology, University of Central Missouri Warrensburg, MO 64093, USA, Tel: (660) 543-8893.

E-mail : sstockton@ucmo.edu

Item

Pretest

Mean ± SD

Posttest

Mean ± SD

Aymp. Sig.

(p <.05)

Pretest; posttest

Run (N=43)(100mx3)

51.37±10.79

51.21±6.02

.011

Grip Strength (n=26)

94.04±21.32

98.98±24.55

.053

Waist (male n=13)

33.77±1.75

33.27±2.13

.043

Waist (female n=13)

30.62±3.03

29.54±2.74

.014

Hip (male n=13)

39.04±3.72

38.54±3.60

.372

Hip (female n=13)

37.65±2.30

36.96±1.76

.057

Remember (N=43)

3.35±.098

3.67±.094

.041

LstnLect

3.25±1.21

3.46±1.03

.117

LstnClass

3.67±1.06

3.90±1.04

.056

LostLect

3.46±1.22

3.53±1.00

.773

NotesLct

3.88±1.11

4.07±1.10

.227

RmrbTold

3.88±1.05

4.04±0.90

.266

DstrcTlk

3.14±1.17

3.49±1.14

.057

Daydream

3.30±1.16

3.40±1.14

.489

SnsLect

4.07±0.98

4.32±0.71

.033

SpknDir

3.93±0.96

4.02±0.80

.501

Undrstnd

4.11±0.79

4.37±0.76

.022

WrdsCnfs

4.40±0.65

4.46±0.59

.513

RptDir

3.60±1.25

3.65±1.23

.869

CnfsSay

3.62±1.17

3.72±1.11

.462

SeeTalk

3.60±0.88

3.67±1.04

.647

TakeNtes

3.88±1.05

3.93±1.06

.624

LseCnctr

3.35±1.17

3.46±0.96

.429

Cncntrte

3.65±1.15

3.70±1.06

.728

PartWrds

3.86±1.12

3.81±1.05

.858

RetainRd

3.46±1.16

3.32±1.15

.235

DistrcRd

2.67±1.27

2.58±1.28

.640

RmbrRd

3.04±1.33

3.44±1.18

.004

ReadTime

2.84±1.46

3.39±1.24

.001

Table 1.   Mean and Standard Deviation Data from Food Elimination Diet Study

Item

Rank

N

Mean Rank

Z

Asym Sig  (p<.05)

GripStr2-GripStrg

Neg.

8

11.38

-1.93

0.053

 

Pos.

17

13.76

 

 

    RunTime2-RunTime

Neg.

30

20.90

-2.55

0.011

      

Pos.

11

21.27

 

 

WaistM2-WaistM

Neg.

5

4

-2.02

0.043

                                   

Pos.

1

1

 

 

WaistF2-WasitF

Neg.

10

7

-2.45

0.014

 

Pos.

2

4

 

 

HipMale2-HipMale

Neg.

6

5

-0.89

0.372

 

Pos.

3

5

 

 

HipFem2-HipFem

Neg.

7

6.57

-1.9

0.057

 

Pos.

3

3

 

 

Remb2-Remember

Neg.

7

10.57

-2.05

0.041

 

Pos.

16

12.63

 

 

LstnLec2-LstnLec

Neg.

9

9

-1.56

0.117

 

Pos.

13

13.23

 

 

LstnCls2-LstnClss

Neg.

6

8.5

-1.91

0.056

 

Pos.

13

10.69

 

 

LostLec2-LostLect

Neg.

9

11.94

-0.29

0.773

 

Pos.

12

10.29

 

 

NotesLec2-NotesLct 

Neg.

6

9.83

-1.21

0.227

 

Pos.

12

9.33

 

 

RembrTld2-Rmrbtld

Neg.

8

10.63

-1.11

0.266

 

Pos.

13

11.23

 

 

DstrcTk2-DstrcTlk

Neg.

8

14.06

-1.91

0.057

 

Pos.

19

13.97

 

 

Daydrm2-Daybream

Neg.

7

10.07

-0.69

0.489

 

Pos.

11

9.14

 

 

SnsLect2-SnsLect

Neg.

3

5.5

-2.14

0.033

 

Pos.

10

7.45

 

 

SpknDir2-SpknDir

Neg.

8

6.94

0.67

0.501

 

Pos.

8

10.06

 

 

Undrstd2-Undrstnd

Neg.

4

8

-2.3

0.022

 

Pos.

13

9.31

 

 

WrdsCnf2-WrdsCnfs Neg.

Neg.

8

9

-0.65

0.513

 

Pos.

10

9.9

 

 

RptDir2-RptDir

Neg.

11

14.23

-0.16

0.869

 

Pos.

14

12.04

 

 

 

 

Item

 

 

Rank

 

 

N

 

 

Mean Rank

 

 

Z

 

 

Asym. Sig (p<.05)

 

 

CnfsSay2-CnfsSay

 

 

Neg.

 

 

9

 

 

9.61

 

 

-0.73

 

 

0.462

 

Pos.

11

11.23

 

 

SeeTalk2-SeeTalk

Neg.

13

17.38

-0.46

0.647

 

Pos.

18

15

 

 

TkeNtes2-TakeNtes

Neg.

11

11.18

-0.49

0.624

 

Pos.

12

12.75

 

 

LseCnct2-CseCnctr

Neg.

12

11.17

-0.79

0.429

 

Pos.

13

14.69

 

 

Cncntrt2-Cncntrte

Neg.

11

11.59

-0.35

0.728

 

Pos.

12

12.38

 

 

PartWrd2-PartWrds

Neg.

14

14

-0.18

0.858

 

Pos.

13

14

 

 

RetnRd2-RetainRd

Neg.

12

11.17

-1.19

0.235

 

Pos.

8

9.5

 

 

DistrRd2-DistrcRd

Neg.

16

12.94

-0.47

0.64

 

Pos.

11

15.55

 

 

RmbrRd2-RmbrRd

Neg.

5

10

-2.87

0.004

 

Pos.

18

12.56

 

 

Rdtime2-ReadTime

Neg.

4

8.5

-3.3

0.001

 

Pos.

19

12.74

 

 

Table 2. Repeat Measure Analysis of Food Elimination Diet Data

Item

Minimum

Maximum Mean

SD

Food Items

Casein

1.14                

11.29

4.50

2.47

Cheese

1.10

10.42

4.56

2.30

Goat Cheese

0.99

6.61

2.52

1.20

Milk

1.17

8.91

3.72

2.00

Moz. Cheese

0.93

9.37

3.18

1.90

Whey

1.28

8.61

4.16

2.07

Yogurt

1.17

9.03

3.73

2.08

Gliadin

1.20

9.82

3.69

1.95

Wheat Gluten

0.98

8.43

3.76

1.72

Wheat

0.95

7.43

3.17

1.78

Candida Items

Candida albicans

1.12

19.21

8.22

4.22

Sugar

1.07

3.47

1.54

0.40

Baker’s Yeast

1.33

13.35

3.94

2.26

Brewer’s Yeast

1.22

12.77

3.22

2.11

Table 3.  Sample results from the Comprehensive IgG Food Allergy Test ™ (N=43)

Food Items Scale=Not Significant 1.00-1.99; Low 2.00-3.49; Moderate 3.50-4.99; and High >5.00 while the ranges for the Candida scale were Not Significant <3.49; Low 3.50-6.99; Moderate 7.00-14.99; and High >15.00.