Integrative Molecular Medicine

An Open Access, Peer Reviewed Journal
NLM ID: 101660036
Online ISSN: 2056-6360

Volume 07, Issue 03


Brain metastasis in HER2 positive stomach cancer

Yasemin Benderli Cihan

Short Communication-Integrative Molecular Medicine (IMM)

May 15, 2020


Potential roles of nitric oxide in COVID-19: A perspective

Achala de Mel

Perspective-Integrative Molecular Medicine (IMM)

May 15, 2020


Inflammatory cardiomyopathy: A review and meta-analysis of pathophysiology, diagnosis and clinical management

Aref Albakri

Review Article-Integrative Molecular Medicine (IMM)

May 25, 2020


The changing molecular landscape of AML and its impact on treatment

Laura Finn Carter Davis Michael Lunski Muhammad Azeem Khan Ashley Staton Ambuga Badari

Review Article-Integrative Molecular Medicine (IMM)

June 30, 2020


SOX30 might not be associated with Sertoli cell-only syndrome in azoospermic Japanese men

Toshinobu Miyamoto Masashi Iijima Takeshi Shin Masafumi Ikezawa Yasuhiro Utsuno Yasuaki Saijo Hiroshi Okada Kazuo Sengoku

Case Report-Integrative Molecular Medicine (IMM)

April 28, 2020


COVID-19: Search for Therapeutics

Ashok Chakraborty Brian Friedrich Jayant Tatake Vijetha Chiniga Rajesh Pandey Preetam Holkar Neelam Holkar Vinod Arora Randall Barton Anil Diwan

Review Article-Integrative Molecular Medicine (IMM)

July 17, 2020


About Journal


Integrative Molecular Medicine is an Open Access peer reviewed international journal. Molecular Medicine journal endeavor to understand normal body functioning and disease pathogenesis at the molecular level, which can enable researchers and physician-scientists to use that knowledge in the design of specific molecular tools for disease diagnosis, treatment, prognosis, and prevention.

Molecular Medicine journal is a peer-reviewed, online open access journal dedicated to a new research discipline at the interface between clinical research and basic biology. Molecular Medicine Journal aim to publish articles that broadly enlighten the biomedicine research community by providing an insight on breakthrough discoveries in basic and clinical medicinal research, thereby lending a strong impetus to this important and rapidly developing field and helping to forge new links between clinicians and molecular biologists.

Molecular Medicine highlights ongoing integrative basic and clinical biomedicines covering fields of biology and medicine. As such the following qualities are essential in any article published by the journal: scientific credibility and rigour, coherence and clarity in the writing. Contributions do not need to be novel as confirmatory and replication studies will be considered, however the article must present new findings, which could include the reporting of negative findings.

The journal, Molecular Medicine provides a new platform for all researchers, scientists, scholars, students to publish their research work and update the latest research information. Molecular Medicine journal publishes research articles as full-length research papers and short reports. In addition, the journal publishes editorials and review articles in innovative formats that target a broad and non-specialized audience.

Molecular Medicine journal provides expert evaluation of the various segments of the broad spectrum of molecular research, the editorial office is assisted by scientists who serve as Associate Editors, editorial board members, and reviewers chosen for their molecular science expertise. They provide constructive evaluation and fair and rapid editorial processing.

Molecular Medicine journal will accept article from the following topics are integrative medical fields including biochemistry, molecular and cell biology, biotechnology, genetics, physiology, endocrinology, signal transduction, cell proliferation, differentiation and development, stem cells and regenerative medicine apoptosis, gene expression, pathology, metabolic disease, genomics, transcriptomics, proteomics, metabolomics of disease, systems medicine, brain disease, cardiovascular biology, diabetes, obesity, osteoporosis, nutrition, pharmacology, toxicology, cancer biology and oncology, epidemiology, genetic medicine, and other medicine-related topics.

Molecular Medicine journal encourage publication of special features. Special features are comprised of a set of manuscripts that address a single theme and include an introductory and summary manuscript. The individual contributions are published in regular issues, and the special feature manuscripts are published as a special issue.

Integrative Molecular Medicine welcomes direct submissions of manuscripts from authors. You can submit your manuscript to: submissions@oatext.com

Copyright is retained by the authors and articles can be freely used and distributed by others. Articles are distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published by IMM, is properly cited.

Ivan Gout


I graduated as an MD at Lviv State Medical University (Ukraine) in 1983 with a great passion to become a surgeon in oncology. Thinking that a PhD in experimental oncology would help to realize my dream, I obtained my doctorate at the Institute of Experimental Oncology, National Academy of Sciences of Ukraine in 1987. A fellowship from the International Agency for Research on Cancer (IARC) took me even further from clinical oncology and also from Ukraine. I arrived in London on the first wave of perestroika and began my post-doctoral training in Jim Woodgett's laboratory at the Ludwig Institute for Cancer Research (UCL Branch). Subsequently, I worked in Mike Waterfield's laboratory at the same Institute studying signal transduction via the PI3 kinase pathway. In 1996, I started my own group at the Ludwig Institute for Cancer Research, focusing on the regulation of growth via the S6 kinase pathway. Since 2003, I have been a Professor in the Department of Biochemistry at UCL – now renamed Structural and Molecular Biology, where I have an active research group working on signal transduction and cellular metabolism in health and disease. I have a strong research (113 papers in peer-reviewed journals, H-Index 52) and patent (10 world-wide patents) portfolio and run two drug discovery programs aimed at developing small molecule inhibitors, targeting ribosomal S6 kinase and Aurora A kinase.

Ricardo H. Alvarez


Dr. Alvarez, a native of Argentina, joined CTCA in October 2014 to lead the company’s global focus on cancer research. He is internationally known for his contribution to breast cancer multidisciplinary management, inflammatory breast cancer, and discovery and monitoring of minimal residual disease in solid tumors. As a medical oncologist, he has focused his clinical career the past two decades on treating patients with the most difficult cases of breast cancer. Prior to joining CTCA, Dr. Alvarez served for five years as an Assistant Professor in the University of Texas MD Anderson Cancer Center Department of Breast Medical Oncology, Division of Cancer Medicine in Houston, Tx. He also served as Assistant Professor at The Morgan Welch Inflammatory Breast Cancer Research Program. His additional experience includes teaching at the Department of Pathology and the Department of Internal Medicine, Universidad Nacional de La Plata, Argentina. He served as Chief, Oncology Section, Hospital Ramon Carrillo - San Carlos de Bariloche, Rio Negro, Argentina, and Instructor, Oncology Consultants P.A., Houston, Tx. He was Secretary of Clinical Oncology Section, School of Oncology, Fundacion Jose Maria Mainetti, Centro Oncologico de Excelencia, Gonnet, Argentina; and Member, Centro Oncologico de Excelencia, Gonnet.

Dr. Alvarez received his medical degree from Universidad Nacional de La Plata - Facultad de Medicina, Argentina. He completed his residency in internal medicine and medical oncology at Centro Oncologico de Excelencia - Gonnet, Argentina. Following completion of his medical oncology training, he pursued additional training in Clinical Pathology to further study molecular diagnostic and serve as Instructor at the Pathology Department with Dr. Pedro Laguens at the Universidad Nacional de La Plata. He also participated in multiple research activities and attended multiple grand rounds with Professors Jose Maria Mainetti and Alberto Luchina, and with several others became leaders in Argentinean oncology. Following his training in Argentina, he moved to Houston to pursue a medical residency in internal medicine at The University of Texas at Houston, and completed a fellowship in hematology and oncology at The University of Texas MD Anderson Cancer Center, Houston, TX. He earned a master’s degree in cancer biology from the Graduate School of Biomedical Sciences at Houston. Dr. Alvarez has received numerous professional awards for his work in cancer research, including T-32 NIH CA009666 in 2006, Award of Excellence in Cancer Research by Texas Medical Society of Oncology in 2008, and the Susan Papizan Dolan Fellowship in Breast Cancer Research in 2008. He has participated in nearly $5 million in research grants and contracts with multiple clinical studies, including several Phase II Investigator Initiated Studies, since 2009 alone.

In 2014, he was Principal Investigator in a study related to monitoring minimal residual disease in locally advanced breast cancer and inflammatory breast cancer by detecting circulating tumor cells. The goal of this study, funded by Sister Institution Fund Network as part of the Global Academy Program Department at MD Anderson, is to identify molecular markers of breast cancer tumor recurrence. This clinical trial is currently active in the U.S., as well as in five academic Institutions across the world, including: INCan in Mexico, INEM in Peru, ClÍnica Alemana in Santiago de Chile, Barretos Hosptial in Brasil, and University of Oslo in Norway. Dr. Alvarez has authored more than 50 articles, abstracts and book chapters and is a frequent presenter at international oncology conferences. His professional memberships include: American Society of Clinical Oncology (ASCO,) American College of Physicians (ACP), American Society of Hematology (ASH), American Association of Cancer Research (AACR), and the Society of Clinical Research Associates (SOCRA). He was a founding member of Grupo de Estudio Tratamiento e Investigacion del Cancer del Sur (GETICS) in Argentina in 1996.

Ioannis John Toliopoulos


Dr. Ioannis John Toliopoulos studied in Chicago, USA, biology (BSc) with full athletic and academic scholarship. Later, he studied the basic sciences in an English Hungarian Medical University and then he returned to Greece where he was granted the PhD. diploma from Ioannina Medical University in the department of clinical laboratorial Physiology in the field of immunodiagnosis and immunotherapy of cancer. Later, he was trained in reproductive medicine, where he was granted the Post Doc diploma in Reproductive and diagnostic immunology. At the end of 2006, he founded a nonprofit foundation called Konstantinion Research Center of Molecular Medicine and Biotechnology, where nowadays he is the president, and develops scientific projects with his team in cancer pathways, autoimmune diseases, and gives solutions to infertile couples. He serves as a reviewer and in editorial board in more than 10 scientific journals, and most of his published research he conducted in the field of immunology of cancer and reproductive immunology.

Ivan Gout


I graduated as an MD at Lviv State Medical University (Ukraine) in 1983 with a great passion to become a surgeon in oncology. Thinking that a PhD in experimental oncology would help to realize my dream, I obtained my doctorate at the Institute of Experimental Oncology, National Academy of Sciences of Ukraine in 1987. A fellowship from the International Agency for Research on Cancer (IARC) took me even further from clinical oncology and also from Ukraine. I arrived in London on the first wave of perestroika and began my post-doctoral training in Jim Woodgett's laboratory at the Ludwig Institute for Cancer Research (UCL Branch). Subsequently, I worked in Mike Waterfield's laboratory at the same Institute studying signal transduction via the PI3 kinase pathway. In 1996, I started my own group at the Ludwig Institute for Cancer Research, focusing on the regulation of growth via the S6 kinase pathway. Since 2003, I have been a Professor in the Department of Biochemistry at UCL – now renamed Structural and Molecular Biology, where I have an active research group working on signal transduction and cellular metabolism in health and disease. I have a strong research (113 papers in peer-reviewed journals, H-Index 52) and patent (10 world-wide patents) portfolio and run two drug discovery programs aimed at developing small molecule inhibitors, targeting ribosomal S6 kinase and Aurora A kinase.

Ricardo H. Alvarez


Dr. Alvarez, a native of Argentina, joined CTCA in October 2014 to lead the company’s global focus on cancer research. He is internationally known for his contribution to breast cancer multidisciplinary management, inflammatory breast cancer, and discovery and monitoring of minimal residual disease in solid tumors. As a medical oncologist, he has focused his clinical career the past two decades on treating patients with the most difficult cases of breast cancer. Prior to joining CTCA, Dr. Alvarez served for five years as an Assistant Professor in the University of Texas MD Anderson Cancer Center Department of Breast Medical Oncology, Division of Cancer Medicine in Houston, Tx. He also served as Assistant Professor at The Morgan Welch Inflammatory Breast Cancer Research Program. His additional experience includes teaching at the Department of Pathology and the Department of Internal Medicine, Universidad Nacional de La Plata, Argentina. He served as Chief, Oncology Section, Hospital Ramon Carrillo - San Carlos de Bariloche, Rio Negro, Argentina, and Instructor, Oncology Consultants P.A., Houston, Tx. He was Secretary of Clinical Oncology Section, School of Oncology, Fundacion Jose Maria Mainetti, Centro Oncologico de Excelencia, Gonnet, Argentina; and Member, Centro Oncologico de Excelencia, Gonnet.

Dr. Alvarez received his medical degree from Universidad Nacional de La Plata - Facultad de Medicina, Argentina. He completed his residency in internal medicine and medical oncology at Centro Oncologico de Excelencia - Gonnet, Argentina. Following completion of his medical oncology training, he pursued additional training in Clinical Pathology to further study molecular diagnostic and serve as Instructor at the Pathology Department with Dr. Pedro Laguens at the Universidad Nacional de La Plata. He also participated in multiple research activities and attended multiple grand rounds with Professors Jose Maria Mainetti and Alberto Luchina, and with several others became leaders in Argentinean oncology. Following his training in Argentina, he moved to Houston to pursue a medical residency in internal medicine at The University of Texas at Houston, and completed a fellowship in hematology and oncology at The University of Texas MD Anderson Cancer Center, Houston, TX. He earned a master’s degree in cancer biology from the Graduate School of Biomedical Sciences at Houston. Dr. Alvarez has received numerous professional awards for his work in cancer research, including T-32 NIH CA009666 in 2006, Award of Excellence in Cancer Research by Texas Medical Society of Oncology in 2008, and the Susan Papizan Dolan Fellowship in Breast Cancer Research in 2008. He has participated in nearly $5 million in research grants and contracts with multiple clinical studies, including several Phase II Investigator Initiated Studies, since 2009 alone.

In 2014, he was Principal Investigator in a study related to monitoring minimal residual disease in locally advanced breast cancer and inflammatory breast cancer by detecting circulating tumor cells. The goal of this study, funded by Sister Institution Fund Network as part of the Global Academy Program Department at MD Anderson, is to identify molecular markers of breast cancer tumor recurrence. This clinical trial is currently active in the U.S., as well as in five academic Institutions across the world, including: INCan in Mexico, INEM in Peru, ClÍnica Alemana in Santiago de Chile, Barretos Hosptial in Brasil, and University of Oslo in Norway. Dr. Alvarez has authored more than 50 articles, abstracts and book chapters and is a frequent presenter at international oncology conferences. His professional memberships include: American Society of Clinical Oncology (ASCO,) American College of Physicians (ACP), American Society of Hematology (ASH), American Association of Cancer Research (AACR), and the Society of Clinical Research Associates (SOCRA). He was a founding member of Grupo de Estudio Tratamiento e Investigacion del Cancer del Sur (GETICS) in Argentina in 1996.

Ioannis John Toliopoulos


Dr. Ioannis John Toliopoulos studied in Chicago, USA, biology (BSc) with full athletic and academic scholarship. Later, he studied the basic sciences in an English Hungarian Medical University and then he returned to Greece where he was granted the PhD. diploma from Ioannina Medical University in the department of clinical laboratorial Physiology in the field of immunodiagnosis and immunotherapy of cancer. Later, he was trained in reproductive medicine, where he was granted the Post Doc diploma in Reproductive and diagnostic immunology. At the end of 2006, he founded a nonprofit foundation called Konstantinion Research Center of Molecular Medicine and Biotechnology, where nowadays he is the president, and develops scientific projects with his team in cancer pathways, autoimmune diseases, and gives solutions to infertile couples. He serves as a reviewer and in editorial board in more than 10 scientific journals, and most of his published research he conducted in the field of immunology of cancer and reproductive immunology.

Editor-in-Chief


Ivan Gout

University College London, UK

Read more

Ricardo H. Alvarez

Cancer Treatment Centers of America, USA

Read more

Ioannis John Toliopoulos

Clinical Laboratory Physiology, Cancer Immunology, Reproductive Immunology
President of Konstantinion Research Center of Molecular Medicine and Biotechnology,
Greece

Read more

Regional Editor-in-Chief


Hans-Peter Deigner (Europe)

Dean, Faculty of Medical & Life Sciences
Professor of Pharmacology
Furtwangen University
Germany

Arnon Blum (Middle East)

Professor of Medicine
Faculty of Medicine
Bar Ilan University
Israel

Editorial Board


Jeremy J. Johnson

Associate Professor
College of Pharmacy
Department of Pharmacy Practice
University of Illinois at Chicago
USA

Anupam Bishayee

Associate Professor & Chair
Department of Pharmaceutical Sciences
School of Pharmacy
American University of Health Sciences

Ali Cyrus Banan

Professor of Medicine & Physiology
Executive Director of Translational Medicine Research University of South Carolina School of Medicine


Rafat A. Siddiqui

Senior Investigator/Director
Cellular Biochemistry Laboratory
Methodist Research Institute
Indiana University Health
Adjunct Professor of Medicine
Department of Medicine
Indiana University School of Medicine

Jennifer Li

Assistant Professor of Histology
Department of Biomedical Sciences
Mercer University School of Medicine

Bruno Sobral

Adjunct Professor
Virginia Bioinformatics Institute at Virginia Tech
Adjunct Professor, Department of Cancer Biology
Wake Forest School of Medicine


Cheng-Jeng Tai

Director/Associate Professor
Division of Hematology and Oncology
Taipei Medical Univesity Hospital

David W. Moskowitz

CEO & Chief Medical Officer
GenoMed, Inc.
ADD IN imm

Sotirios G. Stergiopoulos

Executive Director US Medical Affairs Oncology,
Breast Disease Lead Celgene


Koji Wakame

Hokkaido Pharmaceutical University school of Pharmacy
Japan

De-chu Christopher Tang

Professor
Third Military Medical University
China

Giulio Tarro

Adjunct Professor
Department of Biology
Center for Biotechnology
College of Science and Technology
Temple University
USA


Alireza Heidari

President of American International
Standards Institute (AISI) Irvine California
USA

Mawieh Hamad

Associate Professor
Department of Medical Laboratory Sciences
University of Sharjah

Zoran M Pavlovic

Medical Director CNS
PRA International
Germany


Khalid Siddiqui

Head Biochemistry & Molecular Genetics Lab,
Strategic Center for Diabates Research
King Saud University

Russell Weiner

Executive Director & Head
Merck Clinical Biomarker and Diagnostics Lab

Shahid Siddiqui

Professor of Genetics, Director
Program in Human Genetics & Development
Head, Research Strategy Unit
Faculty of Dentistry and Medicine
Umm-Al-Qura University


Mohamed A. Sabry

Associate Professor
Department of Medical Biochemistry
College of Medicine & Medical Sciences
Arabian Gulf University

Glen J. Weiss

Clinical Associate Professor
Translational Genomics Research Institute (TGen)
Clinical Assistant Professor of Medicine
The University of Arizona College of Medicine-Phoenix
Director of Clinical Research
Cancer Treatment Centers of America

Lilach Soreq

Marie Curie Research Associate
Department of Molecular Neuroscience
UCL Institute of Neurology
United Kingdom


Derek A. Wainwright

Assistant Professor
Department of Neurological Surgery
Northwestern University
Feinberg School of Medicine

Kulvinder Singh Saini

Senior Consultant
Professor of Biotechnology and Genomics
King Abdulaziz University

Tosson Alymorsy

Professor of Parasitology
Faculty of Medicine
Ain Shams University


Tomiyasu Murata

Associate Professor
Departments of Analytical Neurobiology
Faculty of Pharmacy
Meijo University

Vural Fidan

Deputy Director of Otorhinolaryngology Department
Yunus Emre Government Hospital

Faris Q. Alenzi

Professor of Immunology
College of Applied Medical Sciences
Salman bin Abdulaziz University


Ahmed Malki

Associate Professor
Coordinator of Biomedical Science Graduate Program
Department of Health Sciences
College of Arts and Sciences
Qatar University

Omar Bagasra

Professor, Department of Biology
Director
South Carolina Center for Biotechnology
Claflin University

Renee Dufault

Founding Director
Food Ingredient and Health Research Institute


Asim Ahmed Elnour

Adjunct Clinical Associate Professor
Pharmacology Department
Faculty of Medicine and Health Sciences (FMHS)
United Arab Emirates University (UAEU)

Pinar Erkekoglu

Associate Professor of Toxicology
Faculty of Pharmacy
Department of Toxicology
Hacettepe University

Ben Sghaier Mohamed

Laboratory for Forest Ecology
National Institute for Research in Rural Engineering, Water and Forests
University of carthage
Tunisie


Satoru Osuka

Department of Neurosurgery
Winship Cancer Institute
Emory University

Tadaaki Miyazaki

Professor
Department of Probiotics Immunology
Institute for Genetic Medicine
Hokkaido University

William CS Cho

Department of Clinical Oncology
Queen Elizabeth Hospital
Hong Kong


Bin Yang

Associate Professor and Staff Pathologist
Director of Molecular Cytopathology
Director of International Business Development
Pathology & Laboratory Medicine Institute
Cleveland Clinic Lerner College of Medicine

Jon Ver Halen

Associate Professor
Department of Plastic Surgery
Texas A&M School of Medicine

Marco Weiergräber (MD,PhD)

Specialist in Physiology, Director and Professor
Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM))
53175 Bonn, Germany


Ali Gholamrezanezhad, MD, ABR, FEBNM

Department of Radiology
University Hospitals of Cleveland
Case Western Reserve University
Cleveland, Ohio, USA

Andrea Ottonello

Adjunct Professor
Department of Surgical and Diagnostic Integrated Sciences
University of Genoa, Italy

Alessandra Lucchese

Department of Orthodontics
Vita Salute San Raffaele University
Milan, Italy


Antonella Fioravanti

Assistant Professor
Department of Medicine, Surgery and Neuroscience, Rheumatology Unit
University of Siena
Italy

Mohamed Numan

Department of Biochemistry, Microbiology and Bioinformatics
Faculty of Medicine
Université Laval – Quebec City
Canada

Tamer A Gheita

Professor of Rheumatology
Cairo University
Egypt


Randa G.Naffa

Department of Molecular Biology Research Laboratory
Faculty of medicine
The University of Jordan
Jordan

C. Gopi Mohan

Associate Professor
Amrita Centre for Nanosciences and Molecular Medicine
Amrita Institute of Medical Sciences and Research Centre
India

Sanjun Shi

Department of Pharmacy,
Daping Hospital,
Third Military Medical University,
Chongqing
China


Vilda Purutcuoglu

Department of Statistics
Middle East Technical University
Turkey

Yasuhito Shimada, MD, PhD.

Department of Integrative Pharmacology
Mie University Graduate School of Medicine
Japan

Veena N Rao

Professor
Department of OB/GYN
Grady Memorial Hospital
USA


Akikazu Sakudo

Associate Professor
Laboratory of Biometabolic Chemistry
School of Health Sciences
University of the Ryukyus
Japan

Vincent van Ginneken

Chairman & Scientific Director
Blue Green Technologies
The Netherlands

Tetsuya Mine

Department of Medicine
Graduate University of Tokyo School of Medicine
Japan


Plus S Padayatti

Integrative Structural and Computational Biology
Scripps Research Institute
USA

Babatunde Gbolade

Consultant Gynaecologist/Director of Fertility Control Unit St James’s University Hospital, Leeds UK

Yamila García-Martínez

Higher School of Engineering and Technology, Universidad Internacional de La Rioja, Madrid

Ioannis John Toliopoulos

Clinical Laboratory Physiology,
Cancer Immunology, Reproductive Immunology President of Konstantinion Research Center of
Molecular Medicine and Biotechnology,
Greece

Kenan Demirovic

Specialist in Orthodontics and Dentofacial Orthopedics,
Sarajevo Bosnia and Herzegovina

Auric Bhattacharya

Assistant Professor
Department of Oral and
Maxillofacial Surgery. Melaka Manipal Medical College, Malaysia

Asaad Javaid Mirza asaad javaid

Dean of Faculty of Dentistry,
Baqai Medical University,
Karachi Pakistan

Vinay Kumar Bhardwaj

Department Of Public Health Dentistry,
H.P. Govt. Dental College & Hospital,
Shimla, India

Andy H. Choi

Endeavour Australia Cheung Kong Research Fellow
University of Technology, Sydney Australia

Jesús Crespo Sanjuán

Hospital Clínico Universitario de Valladolid,
Spain

Sai Santhoshini Achi

Medical Resident at Harlem Hospital Center,
USA

Xuzhao Zhang

Department of Hematology,
The Second Affiliated Hospital of
Zhejiang University School of Medicine,
China

Giuseppe Bonapace

Research associate at Pediatrics Unit,
University Magna Graecia Catanzaro,
Italy

Christian Barbato

Institute of Biochemistry and Cell Biology (IBBC),
National Research Council (CNR),
Department of Sense Organs,
University Sapienza of Rome,
Italy

Jean Christopher Chamcheu

Assistant Professor,
School Of Basic Pharmaceutical Sciences,
College of Pharmacy,
University of Louisiana Monroe,
USA

Sushant Kachhap

Assistant Professor
Johns Hopkins University School of Medicine
Prostate Cancer/Genitourologic Program, Oncology
The Sidney Kimmel Comprehensive Cancer Center,
USA

In Press


Will be update soon

Current Issue

Volume 8, Issue 2


SOX30 might not be associated with Sertoli cell-only syndrome in azoospermic Japanese men

Toshinobu Miyamoto Masashi Iijima Takeshi Shin Masafumi Ikezawa Yasuhiro Utsuno Yasuaki Saijo Hiroshi Okada Kazuo Sengoku

Case Report-Integrative Molecular Medicine (IMM)

April 28, 2020


COVID-19: Search for Therapeutics

Ashok Chakraborty Brian Friedrich Jayant Tatake Vijetha Chiniga Rajesh Pandey Preetam Holkar Neelam Holkar Vinod Arora Randall Barton Anil Diwan

Review Article-Integrative Molecular Medicine (IMM)

July 17, 2020


NL63: A Better Surrogate Virus for studying SARS-CoV-2

Ashok Chakraborty Anil Diwan

Review Article-Integrative Molecular Medicine (IMM)

July 24, 2020


Comparison of ex-vivo organ culture and cell culture to study drug efficiency and virus-host interactions

Shay Tayeb Yoav Smith Amos Panet Zichria Zakay-Rones

Research Article-Integrative Molecular Medicine (IMM)

September 30, 2020


Right ventricular septal or apical? which is optimal positioning in pacemaker implantation: A systematic review and meta-analysis

Aref Albakri Dieter Bimmel

Review Article-Integrative Molecular Medicine (IMM)

September 30, 2020


Archive


Volume 8

SOX30 might not be associated with Sertoli cell-only syndrome in azoospermic Japanese men

Toshinobu Miyamoto Masashi Iijima Takeshi Shin Masafumi Ikezawa Yasuhiro Utsuno Yasuaki Saijo Hiroshi Okada Kazuo Sengoku

Case Report-Integrative Molecular Medicine (IMM)

April 28, 2020


COVID-19: Search for Therapeutics

Ashok Chakraborty Brian Friedrich Jayant Tatake Vijetha Chiniga Rajesh Pandey Preetam Holkar Neelam Holkar Vinod Arora Randall Barton Anil Diwan

Review Article-Integrative Molecular Medicine (IMM)

July 17, 2020


NL63: A Better Surrogate Virus for studying SARS-CoV-2

Ashok Chakraborty Anil Diwan

Review Article-Integrative Molecular Medicine (IMM)

July 24, 2020


Comparison of ex-vivo organ culture and cell culture to study drug efficiency and virus-host interactions

Shay Tayeb Yoav Smith Amos Panet Zichria Zakay-Rones

Research Article-Integrative Molecular Medicine (IMM)

September 30, 2020


Right ventricular septal or apical? which is optimal positioning in pacemaker implantation: A systematic review and meta-analysis

Aref Albakri Dieter Bimmel

Review Article-Integrative Molecular Medicine (IMM)

September 30, 2020


Brain metastasis in HER2 positive stomach cancer

Yasemin Benderli Cihan

Short Communication-Integrative Molecular Medicine (IMM)

May 15, 2020


Potential roles of nitric oxide in COVID-19: A perspective

Achala de Mel

Perspective-Integrative Molecular Medicine (IMM)

May 15, 2020


Inflammatory cardiomyopathy: A review and meta-analysis of pathophysiology, diagnosis and clinical management

Aref Albakri

Review Article-Integrative Molecular Medicine (IMM)

May 25, 2020


The changing molecular landscape of AML and its impact on treatment

Laura Finn Carter Davis Michael Lunski Muhammad Azeem Khan Ashley Staton Ambuga Badari

Review Article-Integrative Molecular Medicine (IMM)

June 30, 2020


Volume 7

Quantum chemistry molecular modelling for mitochondria targeted chemotherapy: Verification of oxidative stress on mitochondria and anticancer medicines

Shozo Yanagida Susumu Yanagisawa Nobuyuki Murakami

Research Article-Integrative Molecular Medicine (IMM)

March 18, 2020


Superoxide dismutase, glutathione peroxidase and catalase activities in patients with viral hepatitis C

Yalcin MS Gulesci N Bilgin R Koltas IS

Research Article-Integrative Molecular Medicine (IMM)

April 10, 2020


Central and peripheral demyelinating polyneuropathy during Nivolumab treatment in patient with advanced non-small cell lung cancer (NSCLC): A case report

Olga Martelli Mauro Minelli Daniela Bernardo Raffaele Iorio Bianca D. Santomasso Tommaso Verdolotti Mario Sabatelli Francesca Pini

Case report-Integrative Molecular Medicine (IMM)

April 30, 2020


Two genetic disorders (TRMU and SCYL1) explaining transient infantile liver failure in one patient

Teresa Campos Elisa Leão Teles Esmeralda Rodrigues Célia Nogueira Laura Vilarinho Miguel Leão

Case Report-Integrative Molecular Medicine (IMM)

April 30, 2020


A meta-analysis of ECG abnormalities (arrhythmias) in different types of heart failure

Aref Albakri

Review Article-Integrative Molecular Medicine (IMM)

April 28, 2020


A meta-analysis of ECG abnormalities (arrhythmia) in cardiomyopathies

Aref Albakri

Review Article-Integrative Molecular Medicine (IMM)

April 30, 2020


Radiosurgery for symptomatic cavernous malformations in the brainstem

Yoshihisa Kida Toshinori Hasegawa

Research Article-Integrative Molecular Medicine (IMM)

December 16, 2019


Phosphoproteomic profile of peripheral blood mononuclear cells in mesangial proliferative glomerulonephritis patients

Yang Zhang Guoping Sun Fengyan Li Xiaocong Lin Wenbiao Chen Yong Dai

Research Article-Integrative Molecular Medicine (IMM)

February 21, 2020


Zika virus and microcephaly: A review of the molecular interactions

Anne Micaelle Souza Montalvao Bárbara Rezende Teixeira Raquel Barcelos Andrade Laura Gomes Lima Eriston Vieira Gomes

Review Article-Integrative Molecular Medicine (IMM)

February 24, 2020


Emerging diagnostic and predictive utilities of natriuretic peptides in diabetes mellitus patients at high cardiovascular risk

Alexander E Berezin Alexander A Berezin

Mini Review-Integrative Molecular Medicine (IMM)

February 24, 2020


The role of melanocytes in oral mucosa: From embryologic origin to oral mucosal melanoma: A short review

Ricardo Hsieh Raquel Silva Silvia Vanessa Lourenço

Short Review-Integrative Molecular Medicine (IMM)

February 25, 2020


α-Klotho and catalase expression in essential hypertension

Gauri Pathare Sunila Raju Manoj Mashru Vinod Shah Kavita Shalia

Research Article-Integrative Molecular Medicine (IMM)

February 28, 2020


Volume 6

System accuracy evaluation of the systems for self-monitoring of blood glucose GL50 evo and GL 44 following DIN EN ISO 15197:2015: A comparison of accuracy in glucose concentration ranges <100 mg/dL and ≥100 mg/dL

Eckhard Salzsieder Sabine Berg Anselm Puchert Ernst-Joachim Freyse

Review Article-Integrative Molecular Medicine (IMM)

September 30, 2019


Curcumin suppresses an endometrial cell inflammation through inhibition of SREBP-1

So Young Kim Yi Yi Kyaw Mi So Seong Ki Hyung Kim JaeHun Cheong

Research Article-Integrative Molecular Medicine (IMM)

October 16, 2019


Event related potentials (ERPs) and alpha waves in cognition, aging and selected dementias: A source of biomarkers and therapy

Priya Mirand Christopher D Cox Michael Alexander Slav Danev Jonathan Lakey

Research Article-Integrative Molecular Medicine (IMM)

October 25, 2019


The roles of CAM5.2 and caldesmon IHC stains in challenge of diagnosing adenoma, intramucosal carcinoma, and invasive adenocarcinoma on colon biopsies

Yue Jia Ping Ji Luan Nguyen Felicita Baratelli Samuel French

Research Article-Integrative Molecular Medicine (IMM)

October 28, 2019


Quantum chemistry-based verification of antioxidative action of iodide in mitochondria

Shozo Yanagida Akio Kaname Nobuyuki Murakami

Research Article-Integrative Molecular Medicine (IMM)

November 04, 2019


EC-SOD can prevent the chronic stages of pulmonary hypertension induced by hypoxia

Lopez Da Re JM Zaghloul N Kamesh A Rajgarhia A Ochani K Mansoor N Miller EJ Ahmed M

Research Article-Integrative Molecular Medicine (IMM)

November 18, 2019


Spinal cord injury patients with spasticity and pressure sores: Preliminary report on reconstruction with botulinum toxin treated muscle flaps

Luca Negosanti Giorgio Sanguinetti Micaela Battilana Rita Capirossi Siriana Landi Rossella Sgarzani

Research Article-Integrative Molecular Medicine (IMM)

July 31, 2019


Overview of current diagnostic, prognostic, and therapeutic use of EEG and EEG-based markers of cognition, mental, and brain health

Priya Miranda Christopher D Cox Michael Alexander Slav Danev Jonathan RT Lakey

Research Article-Integrative Molecular Medicine (IMM)

August 13, 2019


Expression of the Wnt antagonist Dickkopf-1 in endometriosis

Mariz Kasoha Laura Golbach Panagiotis klavounos Sebastian Findeklee Ingolf Juhasz-Böss Hermann Eichler Erich-Franz Solomayer

Research Article-Integrative Molecular Medicine (IMM)

August 27, 2019


Quantum chemistry molecular modeling for longevity: Importance of antioxidative effects in mitochondria as battery of cells

Shozo Yanagida Kenji Osabe Takeharu Nagai Nobuyuki Murakami

Research Article-Integrative Molecular Medicine (IMM)

August 30, 2019


Impact of a new genetic variant on FVII: C activity

Miolo Gianmaria Caggiari Laura De Zorzi Mariangela Tedeschi Massimo Tessitori Giovanni Percesepe Antonio Santeufemia Davide Adriano Valli De Re Steffan Agostino Corona Giuseppe

Research Article-Integrative Molecular Medicine (IMM)

September 06, 2019


Targeted lipidomics reveals changes in N-acyl serines by acute exposure to an electric field: Molecular insights into the docking of N-18:1 serine interaction with TRPV1 or PPAR-α

Yuzo Nakagawa-Yagi Hiroyuki Hara Takayo Ohto Hiroki Nakanishi Enzo Kawasaki Takahiro Yamaguchi Akikuni Hara

Research Article-Integrative Molecular Medicine (IMM)

September 27, 2019


Cell-free DNA content in human blastocoel fluid-conditioned media differentiates euploid versus aneuploid embryos

Renee J Chosed Arnav Lal Jonathan Blalock T Arthur Chang Randal D Robinson Shawn Zimmerman J David Wininger William E Roudebush

Research Article-Integrative Molecular Medicine (IMM)

June 17, 2019


Osteomyelitis of the pelvic bones in patients with spinal cord injury: Is magnetic resonance useful for preoperative diagnosis?

Sgarzani Rossella Tedeschi Sara Fabio F Trapani Capirossi Rita Battilana Micaela Gaiani Luca Palmonari Massimo Negosanti Luca

Research Article-Integrative Molecular Medicine (IMM)

June 17, 2019


Comparison of the catalytic activities of 5-mer synthetic peptides derived from Box A region of Tob/BTG family proteins against the amyloid-beta fragment peptides

Rina Nakamura Motomi Konishi Youichirou Higashi Motoaki Saito Toshifumi Akizawa

Research Article-Integrative Molecular Medicine (IMM)

June 17, 2019


Unlimited expansion of intestinal stem cells from a wide range of ages

Marcin Duleba Rajasekaran Mahalingam Audrey-Ann Liew Yutao Qi Rahul Neupane Matthew Vincent Suneal Agarwal Francisco A. Sylvester Jeffrey S. Hyams Khek Yu HoJason K. Hou Frank McKeon Wa Xian

Research Article-Integrative Molecular Medicine (IMM)

July 15, 2019


Altered DNA methylation associated with nervosa anorexia in males

Artem Kim Brigitte Izac Nicolas Lebrun Nicolas Ramoz Corinne Blanchet Franck Letourneur Marie Rose Moro Philip Gorwood Marie De Tayrac Thierry Bienvenu

Research Article-Integrative Molecular Medicine (IMM)

July 30, 2019


Holoprosencephaly, proboscis and anophthalmia in a foetus with matUPD14 and trisomy 13. First case to be diagnosed with hysteroscopy: A case report

Lalou Iliana Gkrozou Fani Eleftherios Meridis Tsonis Orestis Paschopoulos Minas Syrrou Marika

Case Report-Integrative Molecular Medicine (IMM)

April 29, 2019


Cardiac TGR5 expression enhanced by hyperglycaemia in diabetic rats: A preclinical warning for disorders with excess bile acids

Feng Yu Kuo Shu Ping Lee Juei-Tang Cheng Ming Chang Wu

Research Article-Integrative Molecular Medicine (IMM)

May 13, 2019


Small molecule inhibition of NOX-1 reduces diabetes conversion in NOD mice

David Taylor Andrew Pearson Lindsey Glenn Kara S Orr Sarah A Tersey David A Taylor-Fishwick

Research Article-Integrative Molecular Medicine (IMM)

May 22, 2019


The influence of albumin on the plasma xanthine oxidoreductase inhibitory activity of allopurinol, febuxostat and topiroxostat: Insight into extra-urate lowering effect

Takashi Nakamura Takayo Murase Etsuko Satoh Atsushi Miyachi Naoyuki Ogawa Naoyuki Ogawa Noriaki Katoh Yukiharu Nakayama

Research Article-Integrative Molecular Medicine (IMM)

May 21, 2019


The Ca2+/calmodulin kinase/AMP-activated protein kinase pathway regulates the lectin phaseolus vulgaris agglutinin induced NO production in human platelets

Maria Grazia Signorello Giuliana Leoncini

Research Article-Integrative Molecular Medicine (IMM)

May 24, 2019


The dynamic molecular landscape of malignant melanomas arising from congenital or common nevi

Olivier Harou Garance Tondeur Françoise Descotes Brigitte Balme Lauriane Depaepe Pierre-Paul Bringuier
Julie Caramel Luc Thomas Stéphane Dalle Jonathan Lopez

Research Article-Integrative Molecular Medicine (IMM)

June 10, 2019


The role of adhesion molecules in nephropathies: The diagnostic applications

Samuel N Uwaezuoke

Review Article-Integrative Molecular Medicine (IMM)

March 11, 2019


Culture medium, extracellular components and differentiation in culturing of human pluripotent stem cells

Hea-Jo Yoon Woo Jung Ho

Short Communication-Integrative Molecular Medicine (IMM)

March 25, 2019


The authenticity, sterility, and stability of culturing human pluripotent stem cells

Hea-Jo Yoon Woo Jung Ho

Short Communication-Integrative Molecular Medicine (IMM)

March 25, 2019


Evolution of stress hormones and proteins in relation to developmental origins of health and disease

Viktor I Goudochnikov

Mini Review-Integrative Molecular Medicine (IMM)

March 25, 2019


Absolute versus relative presentation of tcdB Clostridium difficile biomarker

Ivan Brukner Shaun Eintracht Vincenzo Forgetta Alan Spatz Andreas I Papadakis Matthew Oughton

Short Communication-Integrative Molecular Medicine (IMM)

April 02, 2019


A novel anti-cancer effect of atelocollagen-conjugated miR-520d-5p on pancreatic cancer cells in vitro and in a mouse xenograft model

Yoshitaka Ishihara Yugo Miura Norimasa Miura Keigo Miura

Research Article-Integrative Molecular Medicine (IMM)

April 26, 2019


Breakthrough: PAK1-dependent expression of PD-L1 (programmed death ligand)

Hiroshi Maruta

Opinion-Integrative Molecular Medicine (IMM)

January 18, 2019


Epidermal Growth Factor (EGF) intralesional infiltrations: From the bench to the diabetic ulcers cells

Jorge Berlanga-Acosta Yssel Mendoza-Mari Ariana Garcia-Ojalvo Jose Angel Acosta-Buxado Maday Fernandez-Mayola Gerardo Guillen Nieto

Review Article-Integrative Molecular Medicine (IMM)

February 20, 2019


About mycoplasma infection

Takeo Fuse

Opinion-Integrative Molecular Medicine (IMM)

February 04, 2019


The role of mitochondria in tumorigenesis

Mouza Mohammed AlFashti AlAleeli

Research Article-Integrative Molecular Medicine (IMM)

February 06, 2019


The effect of creatine supplementation on seizure control in children under ketogenic diet. a pilot study

Serafeia Kalamitsou Susan Masino Evangelos Pavlou Maria Gogou Irene Katsanika Kyriaki Papadopoulou-Legbelou Aspasia Serdari Martha Spilioti Athanasios Evangeliou

Research Article-Integrative Molecular Medicine (IMM)

February 08, 2019


Comparative proteomic analysis of the mouse ovary in response to GnIH and GnRH: An in vitro approach

Anushree Dave Michael D. Powell Rajagopala Sridaran Kazuyoshi Tsutsui Amitabh Krishna

Research Article-Integrative Molecular Medicine (IMM)

February 26, 2019


Volume 5

MiR-301a/b function as oncomiRs in non-small-cell lung cancer

Kentaro Jingushi Takayuki Hirono Kaori Kitae Toshiyuki Nagata Masami Sato Kentaro Minami
Masaya Aoki Aya Harada Takeda Tadashi Umehara Hiroshi Egawa Yoshino Nakatsuji Yuko Ueda
Tatsuhiko Furukawa Kazutake Tsujikawa

Research Article-Integrative Molecular Medicine (IMM)

December 14, 2018


Mitochrondrial therapy: A new concept for therapeutic management for tropical diseases

Viroj Wiwanitkit

Editorial-Integrative Molecular Medicine (IMM)

December 20, 2018


Oxidative lipidomics

Onur KoyuncuSedat HakimogluSenem Urfali

Review Article-Integrative Molecular Medicine (IMM)

December 28, 2018


Efficacy of subcutaneous immunotherapy achieved with a whole-body extract of Pseudomyrmex ant. A case reported in a young woman, in Argentina

Raquel M Rodriguez Silvia G Irañeta María L Olgiati Luciana L Soprano Krikor Mouchián Angel Alonso Vilma G Duschak

Case Report-Integrative Molecular Medicine (IMM)

December 31, 2018


Osteoclasts recruitment in internal root resorption associated with external granuloma

Aranka Ilea Viorel Miclăuș Flavia Ruxanda Adina Bianca Boșca Radu Septimiu Câmpian Nausica Bianca Petrescu Anida-Maria BăbțanAnca Ștefania Mesaros

Review Article-Integrative Molecular Medicine (IMM)

October 15, 2018


An interesting case report of a giant bladder calculi in China

Chen Hui Huang Maping Huang Tianhai Yang Xiaoyi Ni JJ Li Qingqing Liu Qiuling Jiang Chonghe Xie Keji

Case Report Article-Integrative Molecular Medicine (IMM)

October 29, 2018


The quantum language of the microRNA gene and anti-cancer: with a dynamic computer simulation of human breast cancer drug resistance

Yoichi Robertus Fujii

Review Article-Integrative Molecular Medicine (IMM)

December 07, 2018


Carnosol, a dietary diterpene from rosemary (Rosmarinus officinalis) activates Nrf2 leading to sestrin 2 induction in colon cells

Miao Yan Bhaskar Vemu Jacob Veenstra Sakina M Petiwala Jeremy J Johnson

Research Article-Integrative Molecular Medicine (IMM)

August 15, 2018


Gene therapy and CNS infant hypotonia

Denis Larrivee

Short Communication-Integrative Molecular Medicine (IMM)

August 20, 2018


GC-MS analysis and antidiabetic potentials of Bridelia Micrantha crude extracts

Adewole Ezekiel Sumera Zubai Ojo Abiodun Onasanya Amos Jamshed Iqbal

Research Article-Integrative Molecular Medicine (IMM)

August 27, 2018


The chronic complex stress combined atherogenic diet accelerates the process of atherosclerosis in mice

Jinyao Liu Ayako Himemiya-Hakucho Xu Liu Koichi Yoshimura Tatsuya Fujimiya

Research Article-Integrative Molecular Medicine (IMM)

August 25, 2018


Evaluation of a human placenta-derived hydrogel to support glucose sensitive insulin secretion in human donor islets

Danuta Sosnowska Kaiwen Ma Lindsey Glenn Yumi Imai Jerry Nadler David A Taylor- Fishwick

Research Article-Integrative Molecular Medicine (IMM)

August 30, 2018


β-Thalassemia and renal complications. A narrative review of pathophysiologic mechanisms

Christos Demosthenous Perla Eleftheriou Chrysa Apostolou Pantelis Sarafidis Vassilios PerifanisEfthimia Vlachaki

Review Article-Integrative Molecular Medicine (IMM)

August 31, 2018


Identification of a novel compound that protects beta cells and islets from dysfunction associated with inflammatory cytokines

Wojciech Grzesik Jessica Weaver Lindsey Glenn Kaiwen Ma Jerry Nadler David A Taylor-Fishwick

Research Article-Integrative Molecular Medicine (IMM)

June 04, 2018


Challenging role of neutrophil extracellular traps in vascular complications of diabetes mellitus

Alexander Berezin

Review Article-Integrative Molecular Medicine (IMM)

June 15, 2018


Visfatin/NAMPT is unrelated to nonalcoholic fatty liver histology but correlates with liver recovery after partial liver resection: Data from a pilot study

Lock JF Sponholz C Hoppe S Docke S Rieger A Birkenfeld AL Pfeiffer AFH Stockmann M Von Loeffelholz C

Research Article-Integrative Molecular Medicine (IMM)

June 22, 2018


The use of whole exome sequencing to identify carriers of Mosaic Variegated Aneuploidy (MVA): A case study

Munirah T Aljaser Shakir Bahzad

Research Article-Integrative Molecular Medicine (IMM)

June 25, 2018


Acute electric field downregulates human plasma immunoreactive interleukin-6 and -1β levels: Molecular mechanisms underlying inflammation alleviation through electric field therapy

Yuzo Nakagawa-Yag Hiroyuki Hara Chisato Kanai Masashi Sato Akikuni Hara

Research Article-Integrative Molecular Medicine (IMM)

September 24, 2018


Brain stem cells and IGF-I: implications in development, regeneration and cancer therapeutics

Silvia J. Bueno Annabelle Trojan Ricardo Santander Alvaro Alvarez Andrea Guzman Carolina Rojas
Juan J Rey Jerzy Trojan

Research Article-Integrative Molecular Medicine (IMM)

February 16, 2019


Breast cancer, chemotherapy and treatments

Li-Pin Kao

Mini Review-Integrative Molecular Medicine (IMM)

February 23, 2018


The value of five - stage combined double - aortic arch incision in prenatal screening of low risk fetus

Shunan Zhang Chu Shen Xin Zhang

Research Article-Integrative Molecular Medicine (IMM)

April 19, 2018


Combination of 2-oxoglutarate/ascorbic acid/5-hydroxy-methyl-furfur-aldehyde/carnosine inhibits protein oxidation during radical exposure of cigarette smoke

Joachim F. Greilberger Reinhold Wintersteiger Ortner Astrid Michaela Greilberger Ralf Herwig

Research Article-Integrative Molecular Medicine (IMM)

April 30, 2018


How to measure the Vitamin-D-synthetic activity of UV lamps used in phototherapy?

Irina P. Terenetskaya

Research Article-Integrative Molecular Medicine (IMM)

April 29, 2018


Abiogenic evolution of aminoacyl-tRNA synthetase

Kozo Nagano

Research Article-Integrative Molecular Medicine (IMM)

April 30, 2018


Effects of memantine on the growth and protein profiles of neuroblastoma cells

Kiyoshi Sekiguchi Masaaki Sato Michiyo K. Yokoyama Toshiyuki Sato Atsuhiro Tsutiya Kazuki Omoteyama Mitsumi Arito Naoya Suematsu Tomohiro Kato Manae S. Kurokawa

Research Article-Integrative Molecular Medicine (IMM)

January 15, 2018


Analysis of proteinic profile in oral lichen planus

Flores-Luna María Guadalupe López-Ávila Beatriz Elizabeth Liceaga-Escalera Carlos Trejo-Iriarte Cynthia Georgina Mario A Rodríguez Gómez-Clavel José Francisco Hernández-López Hegel Rafael García-Muñoz Alejandro

Research Article-Integrative Molecular Medicine (IMM)

January 18, 2018


Absence of bactericidal activity of orally administered wood creosote on human intestinal bacterial flora

Norio Ogata Takanori Miura

Research Article-Integrative Molecular Medicine (IMM)

February24, 2018


Stress/inflammation and pai-1 as stellar processes in the aging and associated pathologies

Lasierra-Cirujeda J Coronel P Aza Pascual-Salcedo MJ Gimeno M Aza Pascual-Salcedo MM Lasierra-Ibañez A Lasala-Aza C

Short Communication Article-Integrative Molecular Medicine (IMM)

February 26, 2018


Orthodontic traction technique: Clinical case report based on literature

Isabella Sabino Maceno Samara Christina dos Santos Leandro Moreira Tempest Idiberto José Zotarelli Filho Carlos Alberto Costa Neves Buchala

Review Article-Integrative Molecular Medicine (IMM)

February 27, 2018


Volume 4

Measurement of oxidative stress parameters, vitamin D and vitamin D binding protein during vitamin D treatment in a patient with amyotrophic lateral sclerosis

Greilberger J Greilberger M Herwig R

Case Report-Integrative Molecular Medicine (IMM)

November 16, 2017


Acetylation-mediated protein complex dissociation as a key step for active transcription of human disease-related genes

Mitsuo Kato

Short Communication-Integrative Molecular Medicine (IMM)

November 23, 2017


Breast cancer genes, breast cancer and FMTVDM-BEST©Ⓟ imaging

Richard M. Fleming Richard M. Fleming Tapan K. Chaudhuri

Letter to Editor-Integrative Molecular Medicine (IMM)

November 23, 2017


A possible role of an interaction of the age at common childhood infections and selected dietary factors at young age, for the later risk of multiple sclerosis

Klaus Lauer Annette Wahl Marcel Geilenkeuser

Letter to Editor-Integrative Molecular Medicine (IMM)

November 23, 2017


Effects of iguratimod on protein profiles of chondrosarcoma cells

Seido Ooka Manae S. Kurokawa Michiyo Yokoyama Mitsumi Arito Toshiyuki Sato Masaaki Sato
Yukiko Takakuwa Kazuki Omoteyama Naoya Suematsu Kimito Kawahata Tomohiro Kato

Review Article-Integrative Molecular Medicine (IMM)

December 14, 2017


Roles of layilin in human synovial fibroblasts revealed by proteomic analysis

Kosuke Shimazaki Mitsumi Arito Toshiyuki Sato Kazuki Omoteyama Masaaki Sato Manae S. Kurokawa
Naoya Suematsu Hisateru Niki Tomohiro Kato

Research Article-Integrative Molecular Medicine (IMM)

December 20, 2017


Conformation, structure, and thermodynamics integrative mechanism related to receptor regulation

Qinyi Zhao

Short Communication-Integrative Molecular Medicine (IMM)

September 11, 2017


Noninvasive vaccination as a casus belli to redeem vaccine value in the face of anti-vaccine movements

De-chu C. Tang

Research Article-Integrative Molecular Medicine (IMM)

September 15, 2017


Molecular insight into the docking of lysophosphatidylethanolamine (lysoPE)-22:6 interaction with GPR119: Acute exposure to an electric field induces changes in human plasma lysoPE-22:6 and lysoPE-20:4 levels

Yuzo Nakagawa-Yagi Hiroyuki Hara Hiroki Nakanishi Chisato Kanai Akikuni Hara

Research Article-Integrative Molecular Medicine (IMM)

September 22, 2017


Combined effect of a probiotic (Bifidobacterium) and a prebiotic (polydextrose) on the fecal microbiota and stool parameters of healthy young women

Seiichiro Aoe Yuta Nakazawa2 Shinji Ohmisya

Research Article-Integrative Molecular Medicine (IMM)

September 22, 2017


An epigenome-wide association study based on cell type-specific whole-genome bisulfite sequencing: Screening for DNA methylation signatures associated with bone mass

Shohei Komaki Hideki Ohmomo Tsuyoshi Hachiya Ryohei Furukawa Yuh Shiwa Mamoru Satoh Ryujin Endo
Minoru Doita Makoto Sasaki Atsushi Shimizu

Research Article-Integrative Molecular Medicine (IMM)

October 12, 2017


The effects of hemodynamics on the inner layers of the aortic wall in patients with a bicuspid aortic valve

Nimrat Grewal Evaldas Girdauskas Marco C. DeRuiter Marie-José Goumans PhD Jan H. Lindeman
Kushtrim Disha Ron Wolterbeek Deborah I.E. Schoor Robert J.M. Klautz Robert E. Poelmann PhD
Adriana C. Gittenberger-de Groot

Research Article-Integrative Molecular Medicine (IMM)

October 23, 2017


DNA methylation pattern in high-grade cervical intraepithelial neoplasia and cancer revealed by genome-wide methylation analysis of cervical DNA

D. Adriana García Martin C. Abba Ignacio Briceño Fabio A. Aristizabal Angel Cid Arregui

Research Article-Integrative Molecular Medicine (IMM)

October 24, 2017


Scientific rationale for integrative and personalised strategies for pancreatic ductal adenocarcinoma management

Peyda Korhan Robert Verkerk William R Critchley

Review Article-Integrative Molecular Medicine (IMM)

October 31, 2017


Easily performed interval exercise induces to increase in skeletal muscle PGC-1α gene expression

Hiroaki Tanaka Seiya Ueno Ryo Aoyagi Yoichi Hatamoto Magdalena Jackowska Keisuke Shiose Yasuki Higaki

Research Article-Integrative Molecular Medicine (IMM)

July 24 2017


Determining factors of the effectiveness of medical rehabilitation of patients with autoimmune thyroiditis

Kurnikova IA Borisova TA Sargar RV

Research Article-Integrative Molecular Medicine (IMM)

July 24, 2017


Importance of D-neuron research in neuropsychiatry

Keiko Ikemoto

Short Communication-Integrative Molecular Medicine (IMM)

July 27, 2017


Future of the pharmaceutical industry in the GCC countries

Abdulaziz Alsaddique

Short Communication-Integrative Molecular Medicine (IMM)

July 27, 2017


A new dissection procedure for learning of echocardiography

Hiromi Suenaga

Research Article-Integrative Molecular Medicine (IMM)

July 28, 2017


A novel Ubc9 -dependent pathway regulates SIRT1- ER-α Axis and BRCA1- associated TNBC lung metastasis

Jingyao Xu Collin Shumate Yulong Qin Vaishali Reddy Yonte Burnam Victoria Lopez Joel Okoli E Shyam P Reddy Veena N Rao

Research Article-Integrative Molecular Medicine (IMM)

July 28, 2017


Receptor Interacting Protein-2 acts as negative regulator for nontypeable Haemophilus influenzae-induced mucin MUC5AC expression

Ashley O’Neill Bohn Kensei Komatsu Shingo Matsuyama Jian-Dong Li

Research Article - Integrative Molecular Medicine (IMM)

August 11, 2017


Phase I/II study of weekly paclitaxel and carboplatin with concurrent radiation therapy in locally advanced non-small-cell lung cancer: Kansai Clinical Oncology Group T0401

Kazufumi Takamatsu Satoshi Marumo Takehisa Takagi Motonari Fukui Kiyoshi Komuta Tadashi Mio Masataka Hirabayashi

Research Article-Integrative Molecular Medicine (IMM)

August 14, 2017


Neutralization of wireless DECT base radiation by novel resonance devices

Peter C. Dartsch Florian M. König

Research Article-Integrative Molecular Medicine (IMM)

August 28, 2017


Iodine status in European women in New Zealand with moderate selenium deficiency

Ljiljana Jowitt Mark Duxbury

Research Article-Integrative Molecular Medicine (IMM)

August 28, 2017


“Brain steatosis” in an obese mouse model during cycles of Famine and Feast the underestimated role of fat (WAT) in brain volume formation

Vincent van Ginneken Evert de Vries Elwin Verheij Jan van der Greef

Research Article-Integrative Molecular Medicine (IMM)

April 24, 2017


Abiogenic evolution of ribonucleic acid as a left-handed helix and its protecting substances on primordial earth – A story about evolution of ribosome and the origin of life

Kozo Nagano

Review Article-Integrative Molecular Medicine (IMM)

April 25, 2017


Moxa Tar, an important source for developing new anti-inflammatory drug

Qian Zeng

Research Article-Integrative Molecular Medicine (IMM)

April 28, 2017


Selenium and thyroid health in NZ European women

Ljiljana Jowitt

Research Article-Integrative Molecular Medicine (IMM)

May 08, 2017


Hunter-prey correlation between migration routes of African buffaloes and early hominids: Evidence for the “Out of Africa” hypothesis

Vincent van Ginneken Aline van Meerveld Tim Wijgerde Elwin Verheij Evert de Vries Jan van der Greef

Hypothesis-Integrative Molecular Medicine (IMM)

May 14, 2017


The clinical evaluation of vertical root fracture after endodontic treatment with mineral trioxide aggregate

Nobuyuki Tani-Ishii Noriko Mutoh Koichiro Muromachi Jiro Suzuki

Research Article-Integrative Molecular Medicine (IMM)

May 26, 2017


Successful treatment of pneumonia-induced severe ARDS complicated with DIC in two infants using recombinant human thrombomodulin

Phan Huu Phuc Ngo Tien Dong Ta Anh Tuan Shoji Kawachi Noriko Nakajima Naoyuki Hirata Akira Ainai Phung Thi Bich Thuy Tran Minh Dien Le Thanh Hai

Case Report-Integrative Molecular Medicine (IMM)

May 30, 2017


From sequence of tumor liberated protein (TLP) to potential targets for diagnosis and therapy

Giulio Tarro

Research Article-Integrative Molecular Medicine (IMM)

June 15, 2017


The effect of a wheelchair designed to prevent forward head posture on swallowing duration and integrated electromyography of suprahyoid muscles

Hiroshi Goda Tatsuo Hatta Hirotoshi Kishigami Tamotsu Ikeda Satomi Yamada Yoshihiko Shibukawa

Research Article-Integrative Molecular Medicine (IMM)

June 26, 2017


Anticancer activity of the “Hardaliye” on HT-29 Cell Line and proliferative activity on CF-1 cell line: Apoptosis and Antioxidant pathway responsive gene expressions

Ozge Kahraman Ilıkkan Oguzhan Doganlar Zeynep Banu Doganlar Pınar Altınoluk Mimiroğlu Asude Soykan Kırbaş

Research Article-Integrative Molecular Medicine (IMM)

June 30, 2017


Delayed anaphylactic reaction to intravenous infusion of ondansetron report of 3 cases

Nesrine BS Haifa R Bouraoui EO Bechir A Emna B Rabiaa A Yosra BY Rawdha S Salem CB Houcem H Abederrahim K Zorgati O

Case Report-Integrative Molecular Medicine (IMM)

March 13, 2017


Acute exposure to an electric field induces changes in human plasma lysophosphatidylcholine (lysoPC)-22:4 levels: Molecular insight into the docking of lysoPC-22:4 interaction with TRPV2

Nakagawa-Yagi Y Hara H Nakanishi H Tasaka T Hara A

Research Article-Integrative Molecular Medicine (IMM)

March 18, 2017


Luteolin-rich chrysanthemum flower extract suppresses baseline serum uric acid in Japanese subjects with mild hyperuricemia

Marina Hirano Shogo Takeda Shoketsu Hitoe Hiroshi Shimoda

Research Article-Integrative Molecular Medicine (IMM)

March 18, 2017


Comparison between developments of emergency medicine services in Saudi Arabia, compare to USA and Canada

Zohair Al Aseri

Research Article-Integrative Molecular Medicine (IMM)

April 06, 2017


Cell death offers exceptional cellular and molecular windows for pharmacological interventions in protozoan parasites

Saeed El-Ashram Rashid mehmood Gungor Cagdas Dincel Ibrahim Al Nasr Xun Suo

Review Article-Integrative Molecular Medicine (IMM)

April 08, 2017


Characterization of the lipid profile post mortem for Type-2 diabetes in human brain and plasma of the elderly with LCMS-techniques: a descriptive approach of diabetic encephalopathy

V van Ginneken E Verheij M Hekman J van der Greef

Research Article-Integrative Molecular Medicine (IMM)

April 10, 2017


Volumetric overload shocks in the patho-etiology of the transurethral resection prostatectomy syndrome and acute dilution hyponatraemia

Nisha Pindoria Salma A Ghanem Khalid A Ghanem Ahmed N Ghanem

Review Article-Integrative Molecular Medicine (IMM)

April 15, 2017


Computational prediction of novel human miRNAs/miRNA target sites in correlation with SNP (rs678653) at 3’UTR of cyclin D1 gene

Nisha Thakur Seemi Farhat Basir Mausumi Bharadwaj Ravi Mehrotra

Research Article-Integrative Molecular Medicine (IMM)

April 17, 2017


Crime, re-offence, and substance abuse of patients with severe mental disorder

Fernando Almeida Diana Moreira

Research Article-Integrative Molecular Medicine (IMM)

April 20, 2017


The plastinated porcine heart specimen for learning echocardiography

Hiromi Suenaga

Research Article-Integrative Molecular Medicine (IMM)

April 21, 2017


Joint Accreditation Committee of the International Society for Cellular Therapy and the European Group for Blood and Marrow Transplantation accreditation for autologous hematopoietic stem cell transplantation in non-leukemic malignancies: burden or benefit?

Huijberts S Baars JW Tinteren HV Holtkamp MJ Rodenhuis S

Commentary-Integrative Molecular Medicine (IMM)

December 29, 2016


Fermented vegetable and fruit extract (OM-X®) stimulates murine gastrointestinal tract cells and RAW264.7 cells in vitro and regulates liver gene expression in vivo

Koji Wakame Akifumi Nakata Keisuke Sato Yoshihiro Mihara Muneaki Takahata Yasuyoshi Miyake Masashi Okada Yoshie Shimomiya Ken-ichi Komatsu

Research Article-Integrative Molecular Medicine (IMM)

January 18, 2017


Proliferation without nuclei suggests mitochondrial cells (MitoCells) to be prokaryotic nature

Nakano K Nakayama T Tachikawa E Mizoguchi E Sasaki K Tarashima M Nakayama N Saito K Osawa M

Research Article-Integrative Molecular Medicine (IMM)

January 26, 2017


Approaching non-canonical STAT3 signaling to redefine cancer therapeutic strategy

Shalini Dimri Sukanya Abhijit De

Review Article-Integrative Molecular Medicine (IMM)

January 30, 2017


Digital pathology: An overview

Saini ML Bouzin C Saini K

Mini review-Integrative Molecular Medicine (IMM)

January 30, 2017


A literature review of issues affecting PrEP Education and Implementation in racism mistrust in black communities (HIV/AIDS)

Cazeau P Jackson R Theodore L Balatien B

Review Article-Integrative Molecular Medicine (IMM)

February 14, 2017


Detection of serum hepatitis B Virus antigen and hepatitis C virus antibody from prostate cancer patients in Japan

Ishiguro H Furuya K Izumi K Nagai T Kawahara T Kubota Y Yao M Uemura H

Research Article-Integrative Molecular Medicine (IMM)

February 14, 2017


Correlation of duration, hypertension and glycemic control with microvascular complications of diabetes mellitus at a tertiary care hospital

Ramnath Santosh Ramanathan, MD

Research Article-Integrative Molecular Medicine (IMM)

February 21, 2017


Volume 3

Effects of serotonin transporter gene polymorphism on mood during the period before the competition in Japanese ballet dancers

Kanaka Yatabe Toshio Kumai Hiroto Fujiya Naoko Yui Satomi Kasuya Yuka Murofushi Keisuke Tateishi Fumiko Terawaki Hajime Kobayashi Aya Uchino Takaaki Kudo Mahiro Ohno Hisao Miyano Tadasu Oyama Haruki Musha

Research Article-Integrative Molecular Medicine (IMM)

November 18, 2016


Is Emilin-1 a molecular link contributing to the extension of thoracic aortic aneurysm dissection and increasing the magnitude of the associated hypertension

Simon W Rabkin

Short Communication-Integrative Molecular Medicine (IMM)

November 18, 2016


Computational tools and interdisciplinary ingenuity for accelerating the development of new medicine

Matthew E. Welsch Sotirios G. Stergiopoulos

Short Communication-Integrative Molecular Medicine (IMM)

November 21, 2016


Aggregation of Sphingosine-DNA and cell construction using components from egg white

Shoshi Inooka

Research Article-Integrative Molecular Medicine (IMM)

November 24, 2016


IgE class switch recombination is regulated by CaMKII via NF-κB alternative pathway

Kano Tanabe Akihiro Goto Akane Maeda Hitomi Sakamoto Ryutaro Kajihara Kohji Fukunaga Seiji Inui

Research Article-Integrative Molecular Medicine (IMM)

November 28, 2016


Science of omics: Perspectives and Prospects for human health care

Nawin Mishra

Review Article-Integrative Molecular Medicine (IMM)

December 05, 2016


Identification of ras/raf binding site and design of interfering peptide with potential clinical application

Tian L Zhang X Nemati F Vallerand D Raimonide C Decaudin D Brossas JY Zini JM Sylvain Choquet S Scoazec MF Feillant M Le Ster K Loisel S Rebollo A

Research Article-Integrative Molecular Medicine (IMM)

December 06, 2016


Comprehensive analysis of surface proteins of peripheral mononuclear blood cells in patients with systemic lupus erythematosus

Nozawa Y Arito M Omoteyama K Sato M Takakuwa Y Ooka S Kurokawa MS Tomohiro Kato

Research Article-Integrative Molecular Medicine (IMM)

December 12, 2016


cAMP-dependent protein kinase A acts as a negative regulator for nontypeable Haemophilus influenzae-induced GM-CSF expression via inhibition of MEK-ERK signaling pathway

Yukihiro Tasaki Wenzhuo Y. Wang Anuhya S. Konduru Kensei Komatsu Shingo Matsuyama Hirofumi Kai Jian-Dong Li

Research Article-Integrative Molecular Medicine (IMM)

December 12, 2016


The evidence of genetic polymorphisms of genes involved in the P2RX7 signaling pathway as predictive biomarkers for response and loss of response to infliximab against Crohn's disease

Araki C Yoshimura M Fukumitsu Y Ma S Ishida T Urabe S Matsushima K Honda T Uehara R Fukuda Y Takeshima F Higuchi N Isomoto H Nakao K Tsukamoto K

Research Article-Integrative Molecular Medicine (IMM)

December 29, 2016


Study on immune changes and correlation of T regulatory cells and IL-35 in the early phase of rat model of acute pancreatitis

Zhuo Yue You Zhao Yang Abu Taiub Mohammed Mohiuddin Chowdhury

Research Article-Integrative Molecular Medicine (IMM)

December 29, 2016


Enhancing mood, relaxation and memories through the TTAP® approach in residents with MCI

Madori LL Balacky C

Research Article-Integrative Molecular Medicine (IMM)

December 29, 2016


Effect of 3-hydroxybutyrate, an endogenous histone deacetylase inhibitor, on FOXO3A mRNA expression in human epithelial colorectal Caco-2 cells: Insight into the epigenetic mechanisms of electric field therapy

Yuzo Nakagawa-Yagi Hiroyuki Hara Hidenori Tsuboi Junji Abe Akikuni Hara

Research Article-Integrative Molecular Medicine (IMM)

September 13, 2016


New scaffolds of inhibitors targeting the DNA binding of NF-κB

Takanobu Kobayashi Sei-ich Tanuma Katsuhito Kino Hiroshi Miyazawa

Research Article-Integrative Molecular Medicine (IMM)

September 19, 2016


Hb Crete in a Turkish Family with Crete Island origin

Duran Canatan İbrahim Keser Türker Bilgen Serpil Delibaş

Short Communication-Integrative Molecular Medicine (IMM)

September 26, 2016


Hypothalamus-pituitary-adrenal (HPA) axis, chronic stress, hair cortisol, metabolic syndrome and mindfulness

Helen Patricia Gaete

Short Communication-Integrative Molecular Medicine (IMM)

October 05, 2016


Metabolic comfort in oncology and free amino acids: perspectives for the use of their regulatory actions in physiological concentrations

Karavay A Karavay P Kaliada T Nefyodov L

Short Communication-Integrative Molecular Medicine (IMM)

October 17, 2016


The effect of trans-resveratrol on the expression of the human DNA-repair associated genes

Fumiaki Uchiumi Jun Arakawa Yutaka Takihara Motohiro Akui Sayaka Ishibashi Sei-ichi Tanuma

Review article-Integrative Molecular Medicine (IMM)

October 20, 2016


Ruptured intracranial dermoid cyst: a case report

Domenico Murrone Bruno Romanelli Aldo Ierardi

Case Report-Integrative Molecular Medicine (IMM)

October 19, 2016


Characterization of small leucine-rich proteoglycans in aortic valves of patients with aortic valve stenosis

Hiroshi Furukawa Masahide Chikada Michiyo K. Yokoyama Mitsumi Arito Manae S. Kurokawa Toshiyuki Sato
Masaaki Sato Kazuki Omoteyama Naoya Suematsu Toshiya Kobayashi Masahiro Sagane Hirotoshi Suzuki Takashi Ando
Tomohiro Kato Tsuyoshi Miyairi

Research Article-Integrative Molecular Medicine (IMM)

October 28, 2016


Exercise, interleukins and bone homeostasis

John Kelly Smith

Short Communication-Integrative Molecular Medicine (IMM)

October 28, 2016


The benefits of incorporating basic sciences and translational research into a pharmacy school curriculum

Rachel R. Miller Gregory S. Gorman

Editorial-Integrative Molecular Medicine (IMM)

October 29, 2016


The Re-Emerging Role of Iron in Infection and Immunity

Mawieh Hamad Khuloud Bajbouj

Commentary Article-Integrative Molecular Medicine (IMM)

October 29, 2016


Investigation of Mutations in Exon 7,8 and Exon 9 of FHIT Gene in Laryngeal Squamous Cell Carcinoma

Nesrin Turaçlar Hasibe Cingilli Vural Şahande Elagöz Emine Elif Altuntaş Fikriye Polat

Research Article-Integrative Molecular Medicine (IMM)

October 31, 2016


Repetitive stretching enhances the formation of neurite swellings in cultured neuronal cells

Hiromichi Nakadate Evrim Kurtoglu Shota Shirasaki Shigeru Aomura

Research Article-Integrative Molecular Medicine (IMM)

August 06, 2016


Anticholinergic activity disappears soon after the prescription of cholinesterase inhibitor

Taishi Koganemaru Koji Hori Misa Hosoi Kimiko Konishi Mitsugu Hachisu Hiroi Tomioka Masayuki Tani Yuka Kitajima Atsuko Inamoto

Case Report-Integrative Molecular Medicine (IMM)

August 09, 2016


Proteomics and molecular medicine

Margaret Simonian

Editorial-Integrative Molecular Medicine (IMM)

August 09, 2016


Distinguishing malignant from benign prostate using Br, Ca, K, Mg, Mn, and Na content in prostatic tissue

Vladimir Zaichick Sofia Zaichick

Research Article-Integrative Molecular Medicine (IMM)

August 10, 2016


DNA microarray analysis of gene expression changes in ICR mouse liver following treatment with active hexose correlated compound

Koji Wakame Akifumi Nakata Keisuke Sato Takehito Miura Anil.D.Kulkarni Marie-Francoise Doursout Alamelu Sundersan Ken-Ich Komatsu

Research Article-Integrative Molecular Medicine (IMM)

August 10, 2016


A bright future for breast and colon cancer patients

Veronica J. James Mark McGovern Peihong Wu Boyang Chang Yankeng Wu

Mini Review-Integrative Molecular Medicine (IMM)

August 18, 2016


Cancer incidence and the biology of extreme old age

Josh Hiller Celeste Vallejo Leo Betthauser James Keesling

Research Article-Integrative Molecular Medicine (IMM)

August 19, 2016


Distinct functional roles of cancerous immunoglobulins in cancer immunology

Gregory Lee

Research Article-Integrative Molecular Medicine (IMM)

August 25, 2016


Antitumor activities of BIBF 1120, BI 860585, and BI 836845 in preclinical models of sarcoma

Yoko Takai Asuka Matsuo Zhiwei Qiao Tadashi Kondo

Research Article-Integrative Molecular Medicine (IMM)

August 26, 2016


Kynurenic acid, an aryl hydrocarbon receptor ligand, is elevated in serum of Zucker fatty rats

Oxenkrug G Cornicelli J van der Hart M Roeser J Summergrad P

Research Article-Integrative Molecular Medicine (IMM)

August 29, 2016


Regulatory role of heat-shock proteins in autoimmune and inflammatory diseases

Cristina Daneri-Becerra Mario D. Galigniana

Research Article-Integrative Molecular Medicine (IMM)

August 22, 2016


Immunotherapy in basal cell carcinoma

Nepton Sheik Khoni GhazalehShoja E Razavi Himakshi Sharma

Research Article-Integrative Molecular Medicine (IMM)

August 22, 2016


Suppressor of cytokine signaling and rheumatoid arthritis

Charles J. Malemud

Research Article-Integrative Molecular Medicine (IMM)

September 05, 2016


Immunotherapy for cancers of the biliary tract

Nepton Sheik Khoni Abdul Rahman El Kinge Abdul Rahman El Kinge

Perspective-Integrative Molecular Medicine (IMM)

August 30, 2016


Clinical potential of DAC-70 sol

Akio Sugitachi Naoko Takahashi Yoshimori Takamori

Research Article-Integrative Molecular Medicine (IMM)

May 12, 2016


Characterization of osteoarthritis in patients with diabetes mellitus type 2

Alexander P Lykov Elena P Trifonova Olga V Sazonova Elena V Zonova

Research Article-Integrative Molecular Medicine (IMM)

May 14, 2016


Stretch-induced functional disorder of axonal transport in the cultured rat cortex neuron

Shigeru Aomura Hiromichi Nakadate Yuma Kaneko Akiyoshi Nishimura Remy Willinger

Research Article-Integrative Molecular Medicine (IMM)

May 18, 2016


Effects of soy peptides on IL-1β-induced matrix-degrading enzymes in human articular chondrocytes

Mitsumi Arito Hiroyuki Mitsui Manae S Kurokawa Kazuo Yudoh Toshikazu Kamada Hisateru Niki Tomohiro Kato

Research Article-Integrative Molecular Medicine (IMM)

May 26, 2016


Cadherin/catenin signaling in developmental biology and pathology

Zen Kouchi

Research Article-Integrative Molecular Medicine (IMM)

May 27, 2016


The canonical Wnt signal paradoxically regulates osteoarthritis development through the endochondral ossification process

Hiroshi Kawaguchi

Short Communication-Integrative Molecular Medicine (IMM)

May 27, 2016


Induction of the expression of GABARAPL1 by hydrogen peroxide in C6 glioma cells

Yoshimitsu Kiriyama Kunihiko Kasai Katsuhito Kino Hiromi Nochi

Research Article-Integrative Cancer Science and Therapeutics (ICST)

June 10, 2016


Anti-aging effects of Lactobacilli

Hisako Nakagawa Tadaaki Miyazaki

Review Article-Integrative Cancer Science and Therapeutics (ICST)

June 13, 2016


Intranasal insulin administration does not modulate incretin secretion, gastric emptying, and appetite in healthy young adults

Yoshikazu Hirasawa Hisayo Yokoyama Nooshin Naghavi Yoshihiro Yamashina Ryosuke Takeda Akemi Ota Daiki Imai Tomoaki Morioka Masanori Emoto Kazunobu Okazaki

Research Article-Integrative Molecular Medicine (IMM)

June 17, 2016


Nrf2 gene as a double-edged sword: Clinical relevance of its genetic polymorphisms

Toshihisa Ishikawa Masaharu Shinkai Takeshi Kaneko

Mini Review-Integrative Molecular Medicine (IMM)

June 22, 2016


Acute appendicitis revisited: computed tomography and ultrasound scan are they necessary to establish a diagnosis?

Osman A Hamour Eman M.Fallatah Rawan O. Alshehri Zain A. Alshareef Halah F.AL-Enizi

Research Article-Integrative Molecular Medicine (IMM)

June 23, 2016


Primary cilia-mediated intercellular signaling in hair follicles

Kazuyuki Matsushima Mika Suematsu Chie Mifude Kuniyoshi Kaseda

Research Article-Integrative Molecular Medicine (IMM)

June 24, 2016


Trophic factors intervention regenerates the nestin-expressing cell population in a model of perinatal excitotoxicity: Implications for perinatal brain injury and prematurity

A. Espinosa-Jeffrey R. A. Arrazola B. Chu A. Taniguchi S. M. Barajas P. Bokhoor J. Garcia A. Feria-Velasco J. de Vellis

Research Article-Integrative Molecular Medicine (IMM)

June 25, 2016


The influence of a passion flower extract on free testosterone in healthy men: a two part investigation involving younger and older men

Richard J. Bloomer John J. MacDonnchadh Trint A. Gunnels John Henry M. Schriefer

Research Article-Integrative Molecular Medicine (IMM)

February 16, 2016


Different associations of premorbid intelligence vs. current cognition with BMI, insulin and diabetes in the homebound elderly

Mkaya Mwamburi Wei Qiao Qiu

Research Article-Integrative Molecular Medicine (IMM)

February 19, 2016


Comparative effect of ultrasound therapy with conventional therapy on breast engorgement in immediate post-partum mothers: A randomized controlled trial

Powar Priyanka Basavaraj C Ramannavar A Geeta Kurhade Arvind Kurhade Angel Justiz-Vaillant Rajarm Powar Sehlule Vuma

Research Article-Integrative Molecular Medicine (IMM)

March 02, 2016


Surgical resection and long-term disease-free survival in stage IIIB non-small cell lung cancer after gefitinib down-staging: a case report

Natella Jafarova Gary Dewar R Petter Tonseth David L. Saltman

Research Article-Integrative Molecular Medicine (IMM)

March 08, 2016


Important high light on diabetes in acute coronary syndrome cases: Saudi Arabia

Khalid A. AlNemer

Research Article-Integrative Molecular Medicine (IMM)

March 09, 2016


Adipose-derived adult stem cells and new technique for intracavernosal injection for erectile dysfunction: novel approach to treat diabetes mellitus. Erectus Shot Technique

Carlos Mercado,MD

Review Article-Integrative Molecular Medicine (IMM)

March 11, 2016


Blockade of the neuropeptide Y Y2 receptor with the potent antagonist BIIE0246 regulates gene expression levels in the lipid metabolic pathways in human hepatoma cell line HepG2

Kaji H Okada M Hamaue A Mori M Nagai M

Research Article-Integrative Molecular Medicine (IMM)

March 16, 2016


Gestational-diabetes-in-New-Zealand-ethnic-groups

Ljiljana M Jowitt

Review Article-Integrative Molecular Medicine (IMM)

March 21, 2016


Hypothalamic mitochondria in energy homeostasis and obesity

Xin Guo Lei Wu Weiqun Wang Denis M Medeiros Stephen Clarke Edralin Lucas Brenda Smith Winyoo Chowanadisai Winyoo Chowanadisai Dingbo Lin

Review Article-Integrative Molecular Medicine (IMM)

March 24, 2016


Acute exposure to an electric field induces changes in human plasma 9-HODE, 13-HODE, and immunoreactive substance P levels: Insight into the molecular mechanisms of electric field therapy

Yuzo Nakagawa-Yagi Hiroyuki Hara Fumiyuki Nakagawa Masashi Sato Akikuni Hara

Research Article-Integrative Molecular Medicine (IMM)

March 31, 2016


Incidence of gastric carcinoma at King Faisal Specialist Hospital- Jeddah Saudi Arabia: a hospital-based study

Raha Alahmadi Osman Hamour Al-Enizi H Tashkandi A

Research Article-Integrative Molecular Medicine (IMM)

April 01, 2016


Diabetes and periodontitis: multidisciplinary management

Harinder S. Sandhu Jaffer A

Research Article-Integrative Molecular Medicine (IMM)

April 05, 2016


Growth hormone releasing peptide-6 (GHRP-6) and other related secretagogue synthetic peptides: A mine of medical potentialities for unmet medical needs

Jorge Berlanga-Acosta Gerardo Guillen Nieto Ernesto Lopez-Mola Luis Herrera-Martinez

Review Article-Integrative Molecular Medicine (IMM)

April 15, 2016


ketamine enhances GluR1 Ser845 phosphorylation in prefrontal cortex

Mingfa Huang Ke Zhang Xiang Cai

Research Article-Integrative Molecular Medicine (IMM)

April 19, 2016


Enhancement of physical fitness by black ginger extract rich in polymethoxyflavones: a double-blind randomized crossover trial

Kazuya Toda Marina Kohatsu Shogo Takeda Norihito Shimizu Hiroshi Shimoda

Research Article-Integrative Molecular Medicine (IMM)

April 23, 2016


Interferon response and virus-host interaction in aspect of microRNAs regulation

Thananya Jinato Kritsada Khongnomnan Emily Johnson Witthaya Poomipak Jarika Makkoch Sunchai Payungporn

Review Article-Integrative Molecular Medicine (IMM)

December 03, 2015


The effects of herbal teas on drug permeability

Akira Nakatsuma Satoshi Wada Junji Kamano Yoshimitsu Kiriyama Katsuhito Kino Masaki Ninomiya

Research Article-Integrative Molecular Medicine (IMM)

December 07, 2015


Pharmacological regulation of bladder cancer by miR-130 family seed-targeting LNA

Hiroshi Egawa Kentaro Jingushi Takayuki Hirono Ryo Hirose Yoshino Nakatsuji Yuko Ueda Kaori Kitae Kazutake Tsujikawa

Research Article-Integrative Molecular Medicine (IMM)

December 08, 2015


For the comments on DNA replication, telomere function and cancer action

Adnan Y. Rojeab

Commentary-Integrative Molecular Medicine (IMM)

December 11, 2015


Diabetes drugs that protect pancreatic β cells

Akira Nakatsuma Yoshimitsu Kiriyama Katsuhito Kino Masaki Ninomiya

Review Article -Integrative Molecular Medicine (IMM)

December 12, 2015


The effect of mild electrical stimulation with heat shock on diabetic KKAy mice

Yukari Kai Yu Tsurekawa Ryosuke Fukuda Kohei Omachi Mariam Piruzyan Yuka Okamoto Keishi Motomura Mary Ann Suico Tsuyoshi Shuto Tatsuya Kondo Eiichi Araki Hirofumi Kai

Research Article-Integrative Molecular Medicine (IMM)

December 17, 2015


Effect of fasting and refeeding on the consequences of myocardial infarction in rats

Alcione Lescano de Souza Junior Christiane Malfitano Diego Figueroa Leandro Eziquiel de Souza Eliane Ignotti Maria Cláudia Irigoyen Rui Curi

Research Article-Integrative Molecular Medicine (IMM)

December 28, 2015


Pathogenesis of idiopathic nephrotic syndrome in children: molecular mechanisms and therapeutic implications

Samuel N Uwaezuoke

Mini Review-Integrative Molecular Medicine (IMM)

December 28, 2015


Cav2.2-mediated signaling in the neural circuits underlying anxiety

Ying Zhou Kimie Niimi Weidong Li Eiki Takahashi

Research Article-Integrative Molecular Medicine (IMM)

December 28, 2015


Mechanical triggering of Wnt3a and beta-catenin in 3D bioreactors: The role of frequency and rhythm

Máximo-Alberto Díez-Ulloa Ramiro Couceiro-Otero

Research Article-Integrative Molecular Medicine (IMM)

January 07, 2016


A new strategy for mitigation of the allergenic activity of ovomucoid in hen eggs and beta-lactoglobulin in cow milk

Jun Kido Natsuko Nishi Sachiko Misumi Tomoaki Matsumoto

Review Article-Integrative Molecular Medicine (IMM)

January 25, 2016


Significance of β-Crosslaps and the tumour markers in diseases of the prostate gland

Lukas J. Becker Gerhard M. Oremek

Research Article-Integrative Molecular Medicine (IMM)

February 28, 2016


The protection effects of different dosages of ulinastatin on myocardial

Yanbo Ling Jianxin Sun

Short Communication -Integrative Molecular Medicine (IMM)

February 5, 2016


Distribution of plexin and neuropilin mRNAs in the cranium and brain stem of chick embryos

Ziaul Haque Qin Pu Ruijin Huang

Research Article-Integrative Molecular Medicine (IMM)

February 15, 2016


Angiotensin II type I receptor blocker, Losartan, inhibits fibrosis in liver by suppressing TGF-beta1 production

Hisanobu Ogata Hideko Noguchi Toshio Ohtsubo Jiyuan Liao Hiroshi Kohara Kazunari Yamada Mutsunori Murahashi Yasuki Hijikata Atsushi Suetsugu Robert M Hoffman Kenzaburo Tani

Research Article-Integrative Molecular Medicine (IMM)

February 15, 2016


A quantum theory of disease, including cancer and aging

Jerry I. Jacobson

Research Article-Integrative Molecular Medicine (IMM)

February 15, 2016


Volume 2

Inhibition of Cav2.2-mediated signaling disrupts conditioned fear extinction

Ying Zhou Kimie Niimi Weidong Li Eiki Takahashi

Research Article-Integrative Molecular Medicine (IMM)

January 07, 2015


Effect of 24,25-dihydroxyvitamin D3 on localization of catalase in chick enterocytes

Yang Zhang Ilka Nemere

Research Article-Integrative Molecular Medicine (IMM)

January 09, 2015


Lack of association between CGRP-related gene polymorphisms and medication overuse headache in migraine patients

Masakazu Ishii Hirotaka Katoh Tatsuya Kurihara Ken-ichi Saguchi Shunichi Shimizu Mitsuru Kawamura

Research Article-Integrative Molecular Medicine (IMM)

January 14, 2015


Effects of Cav2.2 inhibitor on hippocampal spatial short-term cognition

Ying Zhou Kimie Niimi Weidong Li Eiki Takahashi

Research Article-Integrative Molecular Medicine (IMM)

January 19, 2015


Flavonoid glucuronides isolated from spinach inhibit IgE-mediated degranulation in basophilic leukemia RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice

Yuta Morishita Emi Saito Eri Takemura Ryoma Fujikawa Ryohei Yamamoto Masanori Kuroyanagi Osamu Shirota Norio Muto

Research Article-Integrative Molecular Medicine (IMM)

January 27, 2015


The nutritional status of women of the coastal region of the Great East Japan Earthquake disaster area: Three years after

Yuka Kotozaki

Short Report-Integrative Molecular Medicine (IMM)

February 02, 2015


Disruption of spatial cognition by intra-accumbens injection of Cav2.2 inhibitor

Ying Zhou Kimie Niimi Weidong Li Eiki Takahashi

Research Article-Integrative Molecular Medicine (IMM)

February 07, 2015

Review of genomics of Barrett’s esophagus and esophageal adenocarcinoma

Khaled Assim Karkout Amgad El Sherif Mohammed Yaman Dongfeng Tan Sadir Al Rawi

Mini Review-Integrative Molecular Medicine (IMM)

February 18, 2015


A fine structure study on osteogenesis of mesenchymal stem cells cultured with a 3D collagen scaffold

Shunji Kumabe Michiko Nakatsuka Rie Iwai Katsura Ueda Yoshifumi Matsuda Shosuke Morita Yasutomo Iwai

Research Article-Integrative Molecular Medicine (IMM)

March 05, 2015


Mental health as a clinical hallmark of cancer

Manuela Malaguti-Boyle

Review Article-Integrative Molecular Medicine (IMM)

March 12, 2015


Prognostic significance of insulin-like growth factor-II mRNA-binding protein 3 in urological cancers: a systemic review and meta-analysis

Da-wei Sun Ying-yi Zhang Yue Qi Yu-guo Chen Jian Ma Gui-qi Liu Guo-yue Lv

Research Article-Integrative Molecular Medicine (IMM)

March 16, 2015


Cav2.2-mediated NMDA receptor signaling in short-term memory

Ying Zhou Kimie Niimi Weidong Li Eiki Takahashi

Research Article-Integrative Molecular Medicine (IMM)

March 16, 2015


Marine algae Sargassum horneri bioactive factor suppresses proliferation and stimulates apoptotic cell death in human breast cancer MDA-MB-231 cells in vitro

Masayoshi Yamaguchi Toru Matsumoto

Research Article-Integrative Molecular Medicine (IMM)

March 17, 2015


Synergy between depression and Alzheimer’s disease: A spectrum model of genomic vulnerability with therapeutic implications

Roberto Rodrigues Farhan Ahmad George Perry Robert Petersen

Research Article-Integrative Molecular Medicine (IMM)

March 17, 2015


Association analysis of CYP2A6 polymorphism to sudden and unexpected death of infants

Motoki Osawa Yoshihiko Inaoka Masato Nakatome Keiko Miyashita Eriko Ochiai Yu Kakimoto Fumiko Satoh Ryoji Matoba

Research Article-Integrative Molecular Medicine (IMM)

March 23, 2015


Non-invasive scoring systems for predicting NASH in Japan: evidences from Japan Study Group of NAFLD

Yoshio Sumida Yoshio Sumida Atsushi Nakajima Hideyuki Hyogo Saiyu Tanaka Masafumi Ono Hideki Fujii Yuichiro Eguchi Masato Yoneda Takeshi Okanoue Yoshito Itoh Japan Study Group of NAFLD (JSG-NAFLD)

Research Article-Integrative Molecular Medicine (IMM)

April 06, 2015


Evidence-based medicine; climbing a mountain for a better decision-making

Mona O. Mohsen Ahmed M. Malki Hassan Abel Aziz

Review Article-Integrative Molecular Medicine (IMM)

April 12, 2015


Effects of CCCP on the expression of GABARAPL2 in C6 glioma cells

Yoshimitsu Kiriyama Airi Ozaki, Katsuhito Kino Hiromi Nochi

Research Article-Integrative Molecular Medicine (IMM)

April 27, 2015


Blood inorganic mercury is directly associated with glucose levels in the human population and may be linked to processed food intake

Renee Dufault Zara Berg Raquel Crider Roseanne Schnoll Larry Wetsit Wayne Two Bulls Steven G. Gilbert H.M. “Skip” Kingston Mesay Mulugeta Wolle G.M. Mizanur Rahman Dan R. Laks

Research Article-Integrative Molecular Medicine (IMM)

May 02, 2015


Shoulder dystocia among parous parturients: Birth weight differences of the largest prior vaginal delivery and index pregnancy

Suneet P. Chauhan Kenny Choi Everett F. Magann Sharon D. Keiser Jonathan F. Rehberg John C. Morrison

Research Article-Integrative Molecular Medicine (IMM)

May 06, 2015


Generation of inner ear hair cells in vitro from mouse embryonic stem cells

Geping Wu Ling Zhang Guangyin Xu Yan Yu Hongyan Zhu Yan Lv

Research Article-Integrative Molecular Medicine (IMM)

May 08, 2015


A critical evaluation of serum lipase and amylase as diagnostic tests for acute pancreatitis

Sarfaraz Jasdanwala Mark Babyatsky

Review Article-Integrative Molecular Medicine (IMM)

May 12, 2015


Age-related difference in nociceptive behavior of Cav2.1α1 mutant mice, rolling Nagoya

Ying Zhou Kimie Niimi Weidong Li Eiki Takahashi

Research Article-Integrative Molecular Medicine (IMM)

May 17, 2015


Discovery of a novel effect of electric field exposure on human plasma beta-endorphin and interleukin-12 levels: Insight into mechanisms of pain alleviation and defense against infection by electric field therapy

Yuzo Nakagawa-Yagi Hiroyuki Hara Yusuke Yoshida Atsushi Midorikawa Akikuni Hara

Research Article-Integrative Molecular Medicine (IMM)

May 17, 2015


Diagnosis of amyloid-positive mild cognitive impairment using structural magnetic resonance imaging: The worth of multiple regions of interest

Piers Vigers Akihiko Shiino Ikuo Tooyama

Research Article-Integrative Molecular Medicine (IMM)

May 26, 2015


The effect of an alkaline buffered creatine (Kre-Alkalyn®), on cell membrane behavior, protein synthesis, and cisplatin-mediated cellular toxicity

Jeff Golini

Research Article-Integrative Molecular Medicine (IMM)

May 28, 2015


Loss of FAM20A protein induces Amelogenesis Imperfecta in mice

Chunying An Shunji Kumabe Michiko Nakatsuka Katsura Ueda Yoshifumi Matsuda Kentaro Ueno Yasutomo Iwai

Research Article-Integrative Molecular Medicine (IMM)

May 28, 2015


Lipoprotein (a), a principle culprit: Relevance to pathobiology of hypertension, ischemic strokes and implications for novel therapeutic targets, a new puzzle found

Okom Nkili F. C. OFODILE

Review Article-Integrative Molecular Medicine (IMM)

June 04, 2015


Progesterone therapy attenuates fetal brain cytokine levels and improves survival/birth weights in infected rat pups

Christian M. Briery Carl H. Rose Kedra Wallace William A. Bennett Rick W. Martin John C. Morrison

Review Article-Integrative Molecular Medicine (IMM)

June 13, 2015


Color-imaging histodiagnostic approach for cancer

Akio Sugitachi Koki Otsuka Toshimoto Kimura Masanori Hakozaki Mizunori Yaegashi Megumu Kamishima Kohei Kume Yukimi Ohmori Satoshi Nishizuka Akira Sasaki

Research Article-Integrative Molecular Medicine (IMM)

June 14, 2015


Cellular stress after transferring human cornea from in vivo to in vitro milieu: A metabolomic approach

Tomasz Kryczka

Research Article-Integrative Molecular Medicine (IMM)

June 12, 2015


Metabolic changes in donor corneas during cold storage–challenging stereotypes

Tomasz Kryczka Jacek P. Szaflik Jerzy Szaflik Anna Midelfart

Research Article-Integrative Molecular Medicine (IMM)

June 15, 2015


Characterization and analysis of claudin-1 expression in colorectal cancer and its metastases: A pilot study

Wael Al Kattan Abderrahman Ouban Rehana Nawab Omar Al-Obaid

Research Article-Integrative Molecular Medicine (IMM)

June 22, 2015


Clinical applicability of glycated hemoglobin in the evolution of patients with hospital hyperglycemia

Beatriz Dal Santo Francisco Bonamichi João Eduardo Nunes Salles Carolina Ferraz Adriano Namo Cury Rubens Aldo Sargaço

Research Article-Integrative Molecular Medicine (IMM)

June 23, 2015


Single-nucleotide-polymorphism-and-cell-type-dependent-gene-expression-of-neuropeptide-Y2-receptor

Mio Okada Masayo Nagai Akiko Hamaue Maiko Mori Hidesuke Kaji

Research Article-Integrative Molecular Medicine (IMM)

June 26, 2015


Inhibition of Cav2.2-mediated signaling induces sensorimotor gating deficits

Ying Zhou Kimie Niimi Weidong Li Eiki Takahashi

Research Article-Integrative Molecular Medicine (IMM)

June 30, 2015


Proteomic network analysis of human uterine smooth muscle in pregnancy, labor, and preterm labor

Craig Ulrich David R. Quilici Karen A. Schlauch Iain L. O. Buxton

Research Article-Integrative Molecular Medicine (IMM)

July 08, 2015


Screening pre-diabetes and obese women in an early stage of renal dysfucntion from serum 25- hydroxy vitamin D and serum parathormone levels with age, body mass index and fast plasma glucose

Ernest Emilion Richard Emilion

Research Article-Integrative Molecular Medicine (IMM)

July 12, 2015


Genome-wide analysis of differentially expressed long noncoding RNAs induced by low shear stress in human umbilical vein endothelial cells

Shao-Liang Chen Zhi-Mei Wang Zuo-Ying Hu and Bing Li

Research Article-Integrative Molecular Medicine (IMM)

July 29, 2015


Human umbilical cord blood stem cells applied in therapy for ionizing radiation injury

Xinwen Zhang Yujun Xia Chenglong JI

Research Article-Integrative Molecular Medicine (IMM)

August 03, 2015


Clinical pathways of metastatic spinal cord compression: Orthopedics experience based on hospital admissions

Sharifa Ezat Wan Puteh Noraziani Khamis Sabarul Afian Mokhtar

Research Article-Integrative Molecular Medicine (IMM)

August 05, 2015


Antioxidant, antimicrobial and antitumor activity of bacteria of the genus Bifidobacterium, selected from the gastrointestinal tract of human

Prosekov A Dyshlyuk L Milentyeva I Sukhih S Babich O Ivanova S Pavskyi V Shishin M Matskova L

Research Article-Integrative Molecular Medicine (IMM)

August 06, 2015


Blockade of recombinant human IL-6 by tocilizumab suppresses matrix metalloproteinase-9 production in the C28/I2 immortalized human chondrocyte cell line

Evan C. Meszaros Wissam Dahoud Sam Mesiano Charles J. Malemud

Research Article-Integrative Molecular Medicine (IMM)

August 08, 2015


Aspects of interferons (IFNs) interfering with HCV-G1 response

Ilham T Qattan

Review Article-Integrative Molecular Medicine (IMM)

August 11, 2015


Purification of IFNγ-secreting, effector T lymphocytes that induce apoptosis in cancer cells

Adeeb AlZoubi Rahaf AlZoubi Fawzy AlSheyab Farah Khalifeh Mohammed El-Khateeb

Research Article-Integrative Molecular Medicine (IMM)

August 12, 2015


Effects of a Cav2.2 inhibitor on spatial and non-spatial short-term memory

Ying Zhou Kimie Niimi Weidong Li Eiki Takahashi

Research Article-Integrative Molecular Medicine (IMM)

August 22, 2015


Relationships of clinical response to relevant molecular signal during Phase I testing of Aurora Kinase A inhibitor: Retrospective assessment

John Nemunaitis Christopher Blend Gabriel Bien-Willner Meghan Degele Alyssa Roth Stacey Hayes Leah Plato Andrew Guo James Nemunaitis David B. Jackson Neil Senzer

Research Article-Integrative Molecular Medicine (IMM)

August 24, 2015


Impact of weight loss in metabolic profile with reeducation diet in obesity group

Beatriz Dal Santo Francisco Bonamichi Sheila Patricia Lopes Rocha Rafael Bonamichi dos Santos Nanci Merce Nilza Maria Scalissi João Eduardo Nunes Salles

Research Article-Integrative Molecular Medicine (IMM)

August 26, 2015


Association between miR-146a SNP rs2910164 and ischemic stroke in Asian population: a meta-analysis

Xue-qi YANG Jiao ZHANG

Research Article-Integrative Molecular Medicine (IMM)

September 05, 2015


Xenoantibodies to porcine non-galactose α 1,3 galactose antigens in non-human primates cross-react and cause apoptosis to human endothelial cells

Rafael Mañez Isabel Moscoso Cristina Costa Alberto Centeno Eduardo Lopez-Pelaez Natalia Suarez Nieves Domenech

Research Article-Integrative Molecular Medicine (IMM)

September 08, 2015


Cation-π interaction of N,N-Dimethyltryptamine in hydrochloric acid solution characteristic to gastric acid

Andrej Vidak Iva Movre Šapić Vladimir Dananić

Research Article-Integrative Molecular Medicine (IMM)

September 10, 2015


The role of sulforaphane on duchenne muscular dystrophy by activation of Nrf2

Cheng-Cao Sun Jing-Yu Pan Shu-Jun Li De-Jia Li

Mini Review-Integrative Molecular Medicine (IMM)

September 14, 2015


Hypothesis on a signalling system based on molecular vibrations of structure forming macromolecules in cells and tissues

Werner Jaross

Review Article-Integrative Molecular Medicine (IMM)

September 14, 2015


Elevated anthranilic acid plasma concentrations in type 1 but not type 2 diabetes mellitus

Gregory Oxenkrug Marieke van der Hart Paul Summergrad

Review Article-Integrative Molecular Medicine (IMM)

September 25, 2015


Role of Cav2.2-mediated signaling in depressive behaviors

Ying Zhou Kimie Niimi Weidong Li Eiki Takahashi

Research Article-Integrative Molecular Medicine (IMM)

October 05, 2015


Establishment of β-2 microglobulin deficient human iPS cells using CRISPR/Cas9 system

Takehito Sato Hisako Akatsuka Yoshiki Yamaguchi Keiko Miyashita Masafumi Tanaka Tetsuro Tamaki
Masato Ohtsuka Minoru Kimura

Research Article-Integrative Molecular Medicine (IMM)

October 12, 2015


Microarray analysis of long non-coding RNA expression in Ankylosing Spondylitis

Weiguo Sui Huan Li Huiyan He Wen Xue Xin Zhao Yong Dai

Research Article-Integrative Molecular Medicine (IMM)

October 15, 2015


Beyond bone remodeling–emerging functions of osteoprotegerin in host defense and microbial infection

Michiyo Kobayashi-Sakamoto Riyoko Tamai Yusuke Kiyoura

Review Article-Integrative Molecular Medicine (IMM)

October 16, 2015


Clinical validity of our color-imaging histo-diagnosis for cancer

Akio Sugitachi Toshimoto Kimura Koki Otsuka Masanori Hakozaki Mizunori Yaegashi Megumu Kamishima Kohei Kume Satoshi Nishizuka Noriyuki Uesugi Tamotsu Sugai Akira Sasaki

Research Article-Integrative Molecular Medicine (IMM)

October 30, 2015


Enhanced recellularization of renal extracellular matrix scaffold under negative pressure

Satoshi Hachisuka Yuichi Sato Miki Yoshiike Ryuto Nakazawa Hideo Sasaki Tatsuya Chikaraishi

Research Article-Integrative Molecular Medicine (IMM)

October 31, 2015


A paediatric patient with AML M1 and a t(11;19)(q23;p13.1) rearrangement

Lisa Duffy Rong Gong Nyree Cole Donald R. Love Alice M. George

Research Article-Integrative Molecular Medicine (IMM)

November 02, 2015


Stilbene derivatives from melinjo extract have antioxidant and immune modulatory effects in healthy individuals

J. Luis Espinoza Dao Thi An1 Ly Quoc Trung Kayoko Yamada Shinji Nakao Takami

Research Article-Integrative Molecular Medicine (IMM)

November 05, 2015


Combined therapy using fetal stem cells and a complex of physical exercises in treatment of patients with amyotrophic lateral sclerosis

A.A. Sinelnyk M.O. Klunnyk M.P. Demchuk N.S. Sych O.V. Ivankova I.G. Matiyashchuk M.V. Skalozub A.V. Novytska K.I. Sorochynska

Research Article-Integrative Molecular Medicine (IMM)

November 13, 2015


Integration of major histocompatibility complex, methylation, and transcribed ultra-conserved regions analyses in uremia

Jinjun Qiu Huiyan He Weiguo Sui Dong’e Tang Yong Dai

Research Article-Integrative Molecular Medicine (IMM)

November 16, 2015


Prognostication of heart failure development and advance: the role of high-sensitive ST2

Alexander E. Berezin

Short Communication-Integrative Molecular Medicine (IMM)

November 16, 2015


Nasal hygiene in patients with end-stage renal disease

Zhao Fan Baiya Li

Research Article-Integrative Molecular Medicine (IMM)

November 20, 2015


EOLA1 inhibits lipopolysaccharide-induced vascular cell adhesion molecule-1 expression by association with MT2A in endothelial cells

Min Luo Weiling Len Xiaotian Lei Hao Meng Xinshou Ouyang Ziwen Liang

Research Article-Integrative Molecular Medicine (IMM)

November 21, 2015


Current situation of newborn screening for congenital hypothyroidism in China

Juan Liu Yonglin Liu Xia Li Fuyong Jiao

Editorial-Integrative Molecular Medicine (IMM)

November 21, 2015


The genetic variant of COX-2 acts as a potential risk factor of colorectal cancer: evidence from a meta-analysis based on 13461 individuals

Yan Pan Song Gao Qi Qi Luming Liu

Research Article-Integrative Molecular Medicine (IMM)

November 30, 2015


Volume 1

Inaugural Editorial for Integrative Molecular Medicine

Masayoshi Yamaguchi

Editorial-Integrative Molecular Medicine (IMM)

Jul 17, 2014


Role of nutritional factor menaquinone-7 in bone homeostasis and osteoporosis prevention

Masayoshi Yamaguchi

Review Article-Integrative Molecular Medicine (IMM)

Jul 23, 2014


Regucalcin, a novel regulatory protein implicated in obesity and diabetes

Masayoshi Yamaguchi

Review Article-Integrative Molecular Medicine (IMM)

Jul 23, 2014

High waist circumference - A potential risk factor for premature metabolic syndrome in women irrespective of menopausal status

Namrata Chhabra Kuldip Sodhi Sahiba Kukreja Sahil Chhabra Sarah Chhabra Kavish Ramessur

Research Article-Integrative Molecular Medicine (IMM)

September 20, 2014


Detection of DNA methylation of gastric juice-derived exosomes in gastric cancer

Yoshida Y Yamamoto H Morita R OikawaR Matsuo Y Maehata T Nosho K Watanabe Y
Yasuda H Itoh F

Research Article-Integrative Molecular Medicine (IMM)

September 29, 2014


Quest for the development of tooth root/periodontal ligament complex by tissue engineering

Hidefumi Maeda Akifumi Akamine

Review Article-Integrative Molecular Medicine (IMM)

October 01, 2014


Serum concentration of bone morphogenetic proteins (BMPs) is not linked to serum anti-mullerian hormone (AMH) level

Sayaka Ogura-Nose Osamu Yoshino Ikumi Akiyama Yasushi Hirota Tetsuya Hirata Miyuki Harada M
Hisahiko Hiroi KaoriKoga Shigeru Saito Yutaka Osuga Tomoyuki Fujii

Research Article-Integrative Molecular Medicine (IMM)

October 03, 2014


Non-targeted human plasma metabolomics reveals the changes in oleoylethanolamide, a lipid-derived signaling molecule, by acute exposure of electric field

Nakagawa-Yagi Y Hara H Fujimori T Yamaguchi T Midorikawa A Hara A

Research-Integrative Molecular Medicine (IMM)

October 14, 2014

Disulfide-bridged proteins with potential for medical applications: therapeutic relevance, sample preparation and structure – function relationships

Michiro Muraki

Review Article-Integrative Molecular Medicine (IMM)

November 05, 2014


Suppressive effects of EB virus infection on HER2 expression in gastric cancer cells

Ryo Morita Yasutaka Sukawa Hiroyuki Yamamoto Yoshihito Yoshida Ritsuko Oikawa Yasumasa Matsuo Tadateru Maehata Katsuhiko Nosho Yoshiyuki Watanabe Hiroshi Yasuda Fumio Itoh

Research Article-Integrative Molecular Medicine (IMM)

November 05, 2014


Development of a novel approach to enhance the solubility of ftibamzone formulation

Ofonime Udofot Kristen Jaruszewski Shawn Spencer Edward Agyare

Research Article-Integrative Molecular Medicine (IMM)

November 07, 2014


A peptide profile of amniotic fluid in a fetal lamb model of gastroschisis

Kei Ohyama Toshiyuki Sato Kunihide Tanaka Shutaro Manabe Hideki Nagae Mitsumi Arito Nobuko Iizuka Shigeki Kojima Kazuki Omoteyama Yasuji Seki Manae S. Kurokawa Naoya Suematsu Kazuki Okamoto Kevin C. Pring Tomohiro Kato Hiroaki Kitagawa

Research Article-Integrative Molecular Medicine (IMM)

November 17, 2014


Diabetes mellitus is important as a risk factor of atrial fibrillation

Kenichi Aizawa Jun Fujii Yoshinori Seko

Research Article-Integrative Molecular Medicine (IMM)

November 27, 2014


The effects of anesthesia and fetal surgery on the early ovine fetus

Shutaro Manabe Hiroaki Kitagawa Kei Ooyama Yasuji Seki Hideki Nagae Masayuki Takagi Junki Koike Jane Zuccollo Kevin C Pringle

Research Article-Integrative Molecular Medicine (IMM)

December 27, 2014

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The publication charges for Integrative Molecular Medicine are GBP 2590

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Special Issues


Breast Cancer

Editor Affiliation:

Ricardo H. Alvarez
Cancer Treatment Centers of America

Submission date: November 30, 2016
Publication date: January 31, 2017

  • Obstacles to the Medical Revolution

    Editor Affiliation:
    David W. Moskowitz
    MD FACP, Founder and CEO, GenoMed, Inc. (www.genomed.com)

    Submission date: June 30, 2016
    Publication date: August 03, 2016

    Description of the Special Issue: It's widely agreed that molecular medicine will revolutionize the practice of medicine. Few people realize that it's long overdue. Linus Pauling and colleagues published "Sickle Cell Anemia, a Molecular Disease," in the November 1949 issue of Science, but the treatment for sickle cell disease remains unsatisfactory over 65 years later.

    What has been holding up the medical revolution? Papers are solicited on this general topic. They may address any of the following topics, or another that the author feels is equally important:

    1. Problems solving polygenic diseases
    2. Is there a better approach to oncology?
    3. Drug discovery and development in the 21st century
    4. Shifting the healthcare industry to prevention: economic and legal challenges
    5. The role of public health authorities
    6. The role of the media
    7. The role of investors


Characteristics of online treatment seekers interested in a text messaging intervention for problem drinking: adults 51 and older versus middle-aged and younger adults.


Liver targeted therapies for hepatocellular carcinoma prior to transplant: contemporary management strategies.


A review of the impact of obesity on common gastrointestinal malignancies


BRCA1 and BRCA2 mutations and treatment strategies for breast cancer


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