Journal of Clinical Investigation and Studies

An Open Access, Peer Reviewed Journal
Impact-Factor: 0.00*
Online ISSN: 2631-4002

Volume 04, Issue 01


Efficacy and Safety of long-term low-dose clarithromycin in patients with refractory chronic sinusitis after endoscopic sinus surgery: A prospective clinical trial

Chen Han Zhou Bing Huang Qian Li Cheng Wu Yubin Huang Zhenxiao Li Yunxia Qu Jing Xiao Nianci Wang Mingjie

Research Article-Journal of Clinical Investigation and Studies (JCIS)

March 30, 2021


The significance of Bcl-2 expression in breast cancer: a 10-year follow-up study

Xin Huang Qing Zhang Ningxia Wang

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 05, 2021


Utility of mouth rinses and gargling with povidone-iodine in patients with covid-19

Daniel Pablo-Marcos Beatriz Abascal Lara Lloret Manuel Gutierrez Cuadra Nieves Velasco Jesus Aguero Jose Antonio Riancho Carmen Valero

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 17, 2021


Miliary lichenoid lesions: nitidus or planus?

Roberta Vezzoni Yuri Merli Marco Chessa Diego Abbenante Miriam Leuzzi Iria Neri

Case Report-Journal of Clinical Investigation and Studies (JCIS)

August 04, 2021


The worldwide prevalence of ADHD in preterm born children and adolescents

Jihee Kim Marc Landry

Research Article-Journal of Clinical Investigation and Studies (JCIS)

August 04, 2021


About Journal


Journal of Clinical Investigation and Studies is an international, peer- reviewed, open access, online journal that aims to spread knowledge and promote discussion through publication of high quality scientific papers, systematic reviews, meta-analyses, opinion articles and other research materials on all aspects of clinical research and trials related to all disciplines of clinical medicine and medical research.

Journal of Clinical Investigation and Studies publishes reports of high quality studies and researches on any intervention intended for human use such as drugs, devices, new treatment combinations, diagnostic techniques, preventive medicine, behavioral therapies, physical therapies, new surgical procedures and techniques and all other interventions that improve the quality of life for people with chronic illness.

Journal of Clinical Investigation and Studies is also interested in interdisciplinary research work using innovative techniques and combinations of laboratory, clinical and epidemiological methods to develop new drugs or techniques. 

Submissions can include interventional/obervational trial reports, evidence-based medical research reports, review reports, meta-analyses, health policies, retrospective and prospective studies/commentaries, and other clinical studies.

Journal of Clinical Investigation and Studies welcomes direct submissions from authors: Attach your word file with e-mail and send it to: submissions@oatext.com alternatively to: editor.jcis@oatext.com

Please, follow the Instructions for Authors. In the cover letter add the name and e-mail address of 5 proposed reviewers (we can choose them or not).

Copyright is retained by the authors and articles can be freely used and distributed by others. Articles are distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published by Journal of Clinical Investigation and Studies, is properly cited.

Tomoko Hasunuma


Tomoko Hasunuma, MD., PhD., Professor, Department of Kitasato Clinical Research Center, (KCRC) Kitasato University School of Medicine, and also Director, Clinical Trial Center, Department of Research, Kitasato University Kitasato Institute Hospital, is recognized as one of well-known clinical pharmacologist in Japan. She has been experienced numbers of early-phase and later-phase clinical trials as a primary investigator.

She graduated from medical course of Tokyo Women’s Medical University (TWMU) in 1987, and started her internal medicine residency at the same university hospital. After she finished her residency, she started her basic and clinical research on Rheumatology at Rheumatology center of TWMU, then became a research fellow at New England Regional Primate Research Center (now closed) of Harvard University in 1989. Since 1990, she started working as a research associate at Institute of Medical Science, St. Marianna University, Japan, and several reports on etiology and therapy of rheumatoid arthritis. She moved to Kitasato Institute in 1999, and started her clinical research carrier.  She accomplished substantial number of clinical trials as a primary investigator until 2012, when she moved as an assistant professor to clinical division of rheumatology at Toho University school of Medicine, Tokyo. In 2015, she was welcomed to Oita University school of medicine as an associate professor of clinical pharmacology, where she accomplished several clinical studies and also educations for medical and nursery students.

Since 2017, she returned to Kitasato University as a professor of medicine, and now she is continuing clinical studies and investigations. She is also a councilor of Japanese Society of Clinical Pharmacology and Therapeutics, and doing commission works.

Editor-in-Chief


Tomoko Hasunuma

Kitasato University School of Medicine, Japan

Read more

Editorial Board.


Tomoko Hasunuma

Director of Clinical Trial Center
Professor
Kitasato University School of Medicine
Japan

Shunji Yasaki

Director of Department of Neurology
Shin-yurigaoka General Hospital
Japan

Shuxiang GUO

Professor, IEEE Senior Member
Faculty of Engineering
Kagawa University
Japan


Kunio Yui

Professor
Fujita Health University School of Medicine
Japan

Kazuo Hayashi

Chief
Arthritis Center
Fukuoka Wajiro Hospital
Japan

Toshihiro Hatakeyama

Assistant professor
Department of Emergency and Critical Care Medicine Dokkyo Medical University Saitama Medical Center
Japan


Katsuya Ohta

Department of Gastroenterological Surgery
Higashiosaka City Medical Center
Japan

Ana Miranda

Biosciences and Food Technology
RMIT University
Australia

Adilson Da Costa

Department of Dermatology
Sao Paulo State Public Servants Health Care Institute
Public Management Secretariat
Brazil


Balako Gumi

Associate Professor of Epidemiology
Department of Animal & Range Sciences
Bule Hora University
Ethiopia

Raffaele Iorio

Associate Professor of Pediatrics
Department of Translational Medical Science University of Naples Federico II
Italy

Andy Suter

Head of Product Development and Medicine Bioforce AG/ A.Vogel Produkte
Switzerland


Anna Capasso

Professor
Toxicology, Pharmacology and Neurosciences
University of Salerno
Italy

Mustafaoglu Rustem

Department of Neurological Physiotherapy and Rehabilitation
Division of Physiotherapy and Rehabilitation Faculty of Health Sciences, Istanbul University
Turkey

In Press


will be updated soon.

Current Issue

Volume 4, Issue 1


Efficacy and Safety of long-term low-dose clarithromycin in patients with refractory chronic sinusitis after endoscopic sinus surgery: A prospective clinical trial

Chen Han Zhou Bing Huang Qian Li Cheng Wu Yubin Huang Zhenxiao Li Yunxia Qu Jing Xiao Nianci Wang Mingjie

Research Article-Journal of Clinical Investigation and Studies (JCIS)

March 30, 2021


The significance of Bcl-2 expression in breast cancer: a 10-year follow-up study

Xin Huang Qing Zhang Ningxia Wang

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 05, 2021


Utility of mouth rinses and gargling with povidone-iodine in patients with covid-19

Daniel Pablo-Marcos Beatriz Abascal Lara Lloret Manuel Gutierrez Cuadra Nieves Velasco Jesus Aguero Jose Antonio Riancho Carmen Valero

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 17, 2021


Miliary lichenoid lesions: nitidus or planus?

Roberta Vezzoni Yuri Merli Marco Chessa Diego Abbenante Miriam Leuzzi Iria Neri

Case Report-Journal of Clinical Investigation and Studies (JCIS)

August 04, 2021


The worldwide prevalence of ADHD in preterm born children and adolescents

Jihee Kim Marc Landry

Research Article-Journal of Clinical Investigation and Studies (JCIS)

August 04, 2021


Archive


Volume 4

Efficacy and Safety of long-term low-dose clarithromycin in patients with refractory chronic sinusitis after endoscopic sinus surgery: A prospective clinical trial

Chen Han Zhou Bing Huang Qian Li Cheng Wu Yubin Huang Zhenxiao Li Yunxia Qu Jing Xiao Nianci Wang Mingjie

Research Article-Journal of Clinical Investigation and Studies (JCIS)

March 30, 2021


The significance of Bcl-2 expression in breast cancer: a 10-year follow-up study

Xin Huang Qing Zhang Ningxia Wang

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 05, 2021


Utility of mouth rinses and gargling with povidone-iodine in patients with covid-19

Daniel Pablo-Marcos Beatriz Abascal Lara Lloret Manuel Gutierrez Cuadra Nieves Velasco Jesus Aguero Jose Antonio Riancho Carmen Valero

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 17, 2021


Miliary lichenoid lesions: nitidus or planus?

Roberta Vezzoni Yuri Merli Marco Chessa Diego Abbenante Miriam Leuzzi Iria Neri

Case Report-Journal of Clinical Investigation and Studies (JCIS)

August 04, 2021


The worldwide prevalence of ADHD in preterm born children and adolescents

Jihee Kim Marc Landry

Research Article-Journal of Clinical Investigation and Studies (JCIS)

August 04, 2021


Volume 3

Retrospective analysis of complications in anterior cervical discectomy and fusion (ACDF) with use of plate at medium-term follow up

Mahieu Geert Vuylsteke Kristien

Research Article-Journal of Clinical Investigation and Studies (JCIS)

February 20, 2020


Ethical impact of the technology on the healthcare system

Yousefi Rizi Hossein Ali

Research Article-Journal of Clinical Investigation and Studies (JCIS)

June 11, 2020


Non-alcoholic fatty liver disease (NAFLD) in overweight and obese children and adolescents

Ralf Schiel Mario Heinrichs Günter Stein Rolf Bambauer Antje Steveling

Research Article-Journal of Clinical Investigation and Studies (JCIS)

December 31, 2020


Volume 2

A modified open omental plugging of peptic ulcer perforation in a mission hospital, northwestern cameroon

Bamidele Johnson Alegbeleye

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 08, 2019


Estimating the economic burden attributable to some risk factor

FéFernández Hernández Efraín Sánchez González

Research Article-Journal of Clinical Investigation and Studies (JCIS)

September 05, 2019


The Effectiveness of Ferric Carboxymaltose in Childbearing Age with Iron Deficiency Anemia

Alyami A Almohaya A Alburaih D Almurait H Elawad M AlHumaidi A Alsuwaidan S

Research Article-Journal of Clinical Investigation and Studies (JCIS)

September 11, 2019


Volume 1

Effects of hydroxyapatite nanoparticles on liver enzymes and blood components

Gamagedara TP Ziana HF

Mini Review-Journal of Clinical Investigation and Studies (JCIS)

October 08, 2018


In-vitro assessment of hemocompatibility and enzyme compatibility of hydroxyapatite nanoparticles

Gamagedara TP

Mini Review-Journal of Clinical Investigation and Studies (JCIS)

October 08, 2018


Therapy strategies regarding cytokines involvement in the pathogenesis of inflammatory bowel disease

Tsvetelina Velikova

Commentary-Journal of Clinical Investigation and Studies (JCIS)

October 10, 2018


Thrombophilia and multiple thrombosis post pancreatectomy due to insulinoma: Case report

Pablo Weber -Alvarez Luis Alejandro Weber- Sánchez Luis Gerardo Sánchez-Brito

Case Report-Journal of Clinical Investigation and Studies (JCIS)

October 19, 2018


Effect of blood transfusion on central venous oxygen saturation in anemic patients on intensive care unit

Abd-Elsalm WM Elbradie GF El-Shehdawy SR Soliman SM

Research Article-Journal of Clinical Investigation and Studies (JCIS)

December 17, 2018


A clinical study to evaluate the effects of adjunct yogic intervention on pulmonary functions in patients of bronchial asthma

Babita Gulati K Ray A Menon BK Rajkumar

Research Article-Journal of Clinical Investigation and Studies (JCIS)

December 28, 2018


Dilated cardiomyopathy: a review of literature on clinical status and meta-analysis of diagnostic and clinical management

Aref Albakri

Review Article-Journal of Clinical Investigation and Studies (JCIS)

July 02, 2018


Assessment of oxygen saturation levels during a mild hyperbaric chamber treatment

Gonzalez KE Hawkins JR Smith GA Heumann KJ Potochny NS

Research Article-Journal of Clinical Investigation and Studies (JCIS)

August 23, 2018


Analysis of 'Code red trauma calls' promoting the development of a novel cognitive aide for blood product resuscitation

Morton S Perritt E Gorry J Jones C PL Mercer SJ

Research Article-Journal of Clinical Investigation and Studies (JCIS)

August 27, 2018


The neccesity of an anti-fibrotic coctail instead of a drug only

Akif Altinbas

Mini Review-Journal of Clinical Investigation and Studies (JCIS)

September 25, 2018


Proposed ICD-11 complex posttraumatic stress disorder, characteristics and symptoms of adults in an inpatient psychiatric setting: A descriptive study

Stadtmann MP Maercker A Binder J Schnepp W

Research Article-Journal of Clinical Investigation and Studies (JCIS)

September 27, 2018


Pathophysiological mechanisms for the development of gestational diabetes insipidus

Rosa Diaz-Perez Janet E. Davis

Short Communication-Journal of Clinical Investigation and Studies (JCIS)

September 29, 2018


Facile synthesis of hydroxyapatite nanoparticles by a polymer-assisted method: morphology, mechanical properties and formation mechanism

Gamagedara TP Rathnayake UM Rajapakse RMG

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 22, 2018


Index of C-peptide / glucose ratio for Carbo70 can be useful in clinical practice for diabetes

Bando H Ebe K Bando M Yonei Y

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 25, 2018


Is pharmacological treatment of pain harmful or beneficial?

Katsuhiro Toda

Short Communication-Journal of Clinical Investigation and Studies (JCIS)

May 27, 2018


No difference in analgesic effects between non-steroidal anti-inflammatory drugs and acetaminophen at the latest two weeks after injury or surgery

Katsuhiro Toda

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 31, 2018


Validation of the Broca index as the most practical method to calculate the ideal body weight.

Weber-Sanchez Alejandro Velazquez Ortega Sofia Weber-Alvarez Pablo

Research Article-Journal of Clinical Investigation and Studies (JCIS)

June 19, 2018


Ultrasound Characteristics of the Rotator Cable in the Presence of Rotator Cuff Tears

Fady Abdelsayed Hang Yu Hema Choudur

Research Article-Journal of Clinical Investigation and Studies (JCIS)

June 29, 2018


Submit Manuscript


Journal of Clinical Investigation and Studies accepts direct submissions from authors: Attach your word file with e-mail and send it to:submissions@oatext.com  alternatively to: editor.jcis@oatext.com

Publication Charges


Journal of Journal of Clinical Investigation and Studies is an Open Access journal and we do not charge the end user when accessing a manuscript or any article. This allows the scientific community to view, download, distribution of an article in any medium, provided that the original work is properly cited, under the term of "Creative Commons Attribution License". In line with other open access journals we provide a flat fee submission structure on the acceptance of a peer-reviewed article which covers in part the entirety of the publication pathway (the article processing charge). The process includes our maintenance, submission and peer review systems and international editing, publication and submission to global indexing and tracking organisations and archiving to allow instant access to the whole article and associated supplementary documents. We also have to ensure enough investment to secure a sustainable model which ethically, legally and financially stable.

The publication charges for Journal of Clinical Investigation and Studies are USD 400.

Frequently Asked Questions (FAQs)

Why are your charges set at these levels?

All articles published in OA Text are open access. Open Access publishing implies that all readers, anywhere in the world, are allowed unrestricted to full text of articles, immediately on publication in OA Text Journals. The Article Publication Charges pay for the editorial and production costs of the journal, for hosting the website, publishing articles online, preparing HTML , PDF and XML versions of the articles and submitting the articles in electronic citation database like CrossRef.

Our financial goals are to:

  • Recover capitalization costs;
  • Produce sufficient revenue to allow for a sustainable and scalable publishing program, under continuous development;
  • Bend the publication-charge cost downward over time.

Who will pay the APC?

Corresponding author or Co-authors has to make the payment on acceptance of the article.

When should I pay?

Corresponding author or the paying institutions should arrange for the payment once they are notified regarding acceptance of the article. APC is exempted for cases in which a wavier agreement has been made in-prior to submission.

*We request an immediate attention towards the payment as the articles will not be published unless the charges have been paid.

How do I pay?

Authors or institutions can make payments by two modes as per their convenience.

  1. Wire/Bank transfer
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Note: No taxes are included in this charge, taxes will be applicable as per the policies of the country of the payee. Additional transaction charges may be levied on the author.

Can I be eligible for wavier on APC?

The waiver request will be considered on a case-by-case basis, and will be provided accordingly.

*The Waiver requests must be made during the submission process and will not be accepted after  processing of the manuscript.

Do I have to pay if my manuscript is rejected?

No, Article processing charges will not be applicable for articles rejected by the Editorial office.

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No, Article processing charges (APCs) do not include the charges for the reprints. Reprints facility is optional and should be order separately.

Most Viewed

Efficacy and Safety of long-term low-dose clarithromycin in patients with refractory chronic sinusitis after endoscopic sinus surgery: A prospective clinical trial

Chen Han Zhou Bing Huang Qian Li Cheng Wu Yubin Huang Zhenxiao Li Yunxia Qu Jing Xiao Nianci Wang Mingjie

Research Article-Journal of Clinical Investigation and Studies (JCIS)

March 30, 2021


The significance of Bcl-2 expression in breast cancer: a 10-year follow-up study

Xin Huang Qing Zhang Ningxia Wang

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 05, 2021


Utility of mouth rinses and gargling with povidone-iodine in patients with covid-19

Daniel Pablo-Marcos Beatriz Abascal Lara Lloret Manuel Gutierrez Cuadra Nieves Velasco Jesus Aguero Jose Antonio Riancho Carmen Valero

Research Article-Journal of Clinical Investigation and Studies (JCIS)

May 17, 2021


Miliary lichenoid lesions: nitidus or planus?

Roberta Vezzoni Yuri Merli Marco Chessa Diego Abbenante Miriam Leuzzi Iria Neri

Case Report-Journal of Clinical Investigation and Studies (JCIS)

August 04, 2021


The worldwide prevalence of ADHD in preterm born children and adolescents

Jihee Kim Marc Landry

Research Article-Journal of Clinical Investigation and Studies (JCIS)

August 04, 2021


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